3948-42-3Relevant articles and documents
Iridium-catalyzed addition of acid chlorides to terminal alkynes
Iwai, Tomohiro,Fujihara, Tetsuaki,Terao, Jun,Tsuji, Yasushi
supporting information; experimental part, p. 6668 - 6669 (2009/10/30)
(Chemical Equation Presented) An iridium N-heterocyclic carbene (NHC) complex, IrCl(cod)(IPr), successfully catalyzed an addition of common aromatic acid chlorides to terminal alkynes to afford (Z)-β-chloro-α,β- unsaturated ketones regio- and stereoselectively. When the NHC ligand (IPr) was changed to a phosphine (RuPhos), the addition occurred with decarbonylation to give the corresponding (Z)-vinyl chlorides. Furthermore, the former reaction using IrCl(cod)(IPr) can be applied to the catalytic synthesis of 2,5-disubstituted furans.
A convenient route to aryl substituted chloro and bromo olefins
Kumaraswamy, Sudha,Kumara Swamy
, p. 2183 - 2184 (2007/10/03)
A wide range of aryl substituted chloro and bromo olefins has been prepared by treating α-chloro and α-bromophosphonates derived from 1-hydrido-5,5-dimethyl-1,3,2-dioxaphosphorinane with sodium hydride in THF at 0°C followed by an aldehyde.