395-07-3 Usage
Functional Groups
Fluoro-substituted phenyl group, 1,2-dione 2-oxime
Usage
Organic synthesis, pharmaceutical research
Potential Applications
Development of new drugs, building block for synthesis of other organic compounds
Biological and Pharmacological Activities
Unknown, but of interest for research
Chemical Structure
Contains a fluorine atom attached to a phenyl ring, a propane chain with a 1,2-dione group, and an oxime functional group
Importance
Valuable tool for scientists and researchers in chemistry and medicine
Research Focus
Investigating its potential as a drug candidate or intermediate in the synthesis of other compounds
Safety
Unknown, but should be handled with care due to its potential reactivity and unknown biological effects
Stability
Unknown, but likely sensitive to heat, light, and moisture due to the presence of the oxime functional group
Check Digit Verification of cas no
The CAS Registry Mumber 395-07-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 395-07:
(5*3)+(4*9)+(3*5)+(2*0)+(1*7)=73
73 % 10 = 3
So 395-07-3 is a valid CAS Registry Number.
395-07-3Relevant articles and documents
Nitrosocarbonyl-Henry and Denitration Cascade: Synthesis of α-Ketoamides and α-Keto Oximes
Reddy, Mallu Kesava,Mallik, Sumitava,Ramakrishna, Isai,Baidya, Mahiuddin
supporting information, p. 1694 - 1697 (2017/04/11)
An unprecedented Henry reaction of in situ generated nitrosocarbonyl intermediates and concomitant denitration cascade has been developed. The reaction is catalyzed by organic base at room temperature offering α-ketoamides, a demanding scaffold for drug discovery, in high yields. An alteration of substitution pattern also produced α-keto oximes, a high-value synthon. The protocol features operational simplicity and broad substrate scope.
