39513-27-4 Usage
Description
2H-Benzimidazol-2-one,5-acetyl-1,3-dihydro-(9CI) is a chemical compound with the molecular formula C10H10N2O2. It is a derivative of benzimidazole, a fused heterocyclic compound. 2H-Benzimidazol-2-one,5-acetyl-1,3-dihydro-(9CI) exhibits biological activities such as anti-inflammatory and analgesic properties, and may also have antifungal and antitumor effects. Its 5-acetyl substitution contributes to its biological activity, making it a promising candidate for further research and development in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
2H-Benzimidazol-2-one,5-acetyl-1,3-dihydro-(9CI) is used as a pharmaceutical agent for its anti-inflammatory and analgesic properties. It may be employed in the development of drugs to treat inflammatory conditions and pain.
Used in Antifungal Applications:
2H-Benzimidazol-2-one,5-acetyl-1,3-dihydro-(9CI) is used as an antifungal agent, potentially effective against various fungal infections.
Used in Antitumor Applications:
2H-Benzimidazol-2-one,5-acetyl-1,3-dihydro-(9CI) is used as an antitumor agent, showing potential in the treatment of cancer.
Used in Treatment of Inflammatory and Autoimmune Diseases:
2H-Benzimidazol-2-one,5-acetyl-1,3-dihydro-(9CI) is used as a therapeutic agent for the treatment of inflammatory and autoimmune diseases, due to its potential to modulate immune responses and reduce inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 39513-27-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,5,1 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 39513-27:
(7*3)+(6*9)+(5*5)+(4*1)+(3*3)+(2*2)+(1*7)=124
124 % 10 = 4
So 39513-27-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H8N2O2/c1-5(12)6-2-3-7-8(4-6)11-9(13)10-7/h2-4H,1H3,(H2,10,11,13)
39513-27-4Relevant articles and documents
Synthesis and structure-activity relationship of aminoarylthiazole derivatives as potential potentiators of the chloride transport defect in cystic fibrosis
Liessi, Nara,Pesce, Emanuela,Salis, Annalisa,Damonte, Gianluca,Tasso, Bruno,Cichero, Elena,Pedemonte, Nicoletta,Millo, Enrico
, p. 646 - 657 (2021/04/02)
Background: Cystic fibrosis (CF) is the autosomal recessive disorder most common in Caucasian populations. It is caused by mutations in the cystic fibrosis transmembrane regulator protein (CFTR). CFTR is predominantly expressed at the apical plasma membra
FRIDEL-CRAFTS ACYLATION OF BENZIMIDAZOLIN-2-ONES WITH ALIPHATIC ACID CHLORIDES
Kadyrov, Ch. Sh.,Khalikov, S. S.
, p. 658 - 661 (2007/10/02)
The acylation of benzimidazolin-2-one and its 5,6-disubstituted derivatives with aliphatic acid chlorides in the presence of anhydrous aluminium chloride was studied.The corresponding 5(6)-acyl-, 5-R-6-acyl, and 5,6-dimethyl-4-acylbenzimidazolin-2-ones, the structures of which were confirmed by the results of elementary analysis and IR, PMR, and mass spectroscopy, were obtained.The yields of the acylation products depend on the electronic effects of the substituents in the benzene ring of the benzimidazolin-2-one on steric factors.
