395639-63-1 Usage
Description
1-(4-Bromo-2-fluorophenyl)-3-chloro-1-propanone, also known as 4'-Bromo-2-fluoro-3'-chloropropiophenone, is a chemical compound with the formula C9H7BrClFO. It is a pale yellow liquid that is recognized for its versatile reactivity and is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. Due to its potential applications in medicinal chemistry, it has been the subject of numerous studies. However, it is crucial to handle and store this chemical with care, as it can be harmful if ingested, inhaled, or comes into contact with skin or eyes.
Uses
Used in Pharmaceutical Industry:
1-(4-BroMo-2-fluorophenyl)-3-chloro-1-propanone is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its versatile reactivity allows for the creation of a wide range of compounds with potential medicinal properties.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(4-BroMo-2-fluorophenyl)-3-chloro-1-propanone is utilized as an intermediate in the production of various agrochemicals, contributing to the development of new compounds for agricultural applications.
Used in Organic Chemistry Research:
1-(4-BroMo-2-fluorophenyl)-3-chloro-1-propanone is also used as a research compound in organic chemistry, where its potential applications in medicinal chemistry are explored. Its unique properties make it a valuable tool for studying new reactions and synthesizing novel organic compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 395639-63-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,9,5,6,3 and 9 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 395639-63:
(8*3)+(7*9)+(6*5)+(5*6)+(4*3)+(3*9)+(2*6)+(1*3)=201
201 % 10 = 1
So 395639-63-1 is a valid CAS Registry Number.
395639-63-1Relevant articles and documents
HETEROARYL PYRIDONE AND AZA-PYRIDONE AMIDE COMPOUNDS
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, (2015/01/16)
Heteroaryl pyridone and aza-pyridone amide compounds of Formula (I) are provided, and various substituents including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk, and for treating cancer and immune disorders such as inflammation mediated by Btk. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
NEW ARYL-BENZOCYCLOALKYL AMIDE DERIVATIVES
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, (2013/03/26)
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.
Inhibitors of Bruton's Tyrosine Kinase
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Page/Page column 140, (2010/09/07)
This application discloses 5-phenyl-1H-pyridin-2-one, 6-phenyl-2H-pyridazin-3-one, and 5-Phenyl-1H-pyrazin-2-one derivatives according to generic Formulae I-III: wherein, variables Q, R, X, X′, Y1, Y2, Y2′, Y3, Y4, Y5, m, and n are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are further useful to treat inflammatory and auto immune diseases associated with aberrant B-cell proliferation such as rheumatoid arthritis. Also disclosed are compositions containing compounds of Formulae I-III and at least one carrier, diluent or excipient.
