395683-39-3

Basic information

• Product Name: Cyclopropanecarboxylic acid, 2-(4-chlorophenyl)-, ethyl ester, (1R,2S)-
• CAS NO: 395683-39-3
• Molecular Formula: C12H13ClO2
• Molecular Weight: 224.687
• Mol File: 395683-39-3.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Cyclopropanecarboxylic acid, 2-(4-chlorophenyl)-, ethyl ester, (1R,2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid, 2-(4-chlorophenyl)-, ethyl ester, (1R,2S)-(395683-39-3)
• EPA Substance Registry System: Cyclopropanecarboxylic acid, 2-(4-chlorophenyl)-, ethyl ester, (1R,2S)-(395683-39-3)

Safety Data

• Hazardous Substances Data: 395683-39-3(Hazardous Substances Data)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 1073-67-2 4-vinylbenzyl chloride 

Relevant articles and documents

Semi-Rationally Designed Short Peptides Self-Assemble and Bind Hemin to Promote Cyclopropanation

The self-assembly of short peptides gives rise to versatile nanoassemblies capable of promoting efficient catalysis. We have semi-rationally designed a series of seven-residue peptides that form hemin-binding catalytic amyloids to facilitate enantioselect

Continuous flow asymmetric cyclopropanation reactions using Cu(i) complexes of Pc-L* ligands supported on silica as catalysts with carbon dioxide as a carrier

Continuous flow heterogeneous asymmetric cyclopropanations catalysed by supported hydrogen-bonded (SHB) chiral copper(i) complexes of pyridine containing tetraazamacrocyclic ligands Pc-L* using CO2 as a transport vector are described. The catalytic system showed high stability and good recyclability without loss of activity for at least 24 h in CO2 and catalyst turnover numbers up to 440 were obtained with excellent conversion (up to 99%) and high selectivity (up to 88%). No leaching of copper was observed. Cyclopropane products from both aromatic and aliphatic olefins were obtained in good yields with enantiomeric excesses up to 72%. This journal is the Partner Organisations 2014.

Silica "sHB" chiral Pc-L* copper complexes for halogen-free solvent cyclopropanation reactions

The grafting of the preformed Pc-L* (pyridine containing macrocyclic ligands) copper(i) complexes on different ordered and non-ordered silicas, and their use, under heterogeneous batch conditions, as catalysts for the olefin cyclopropanation are reported.