39604-80-3

Basic information

• Product Name: Ethanone, 1-[2-hydroxy-4-(phenylmethoxy)phenyl]-2-phenyl-
• Synonyms: 2-hydroxy-4-benzyloxydesoxybenzoin;1-[2-hydroxy-4-(phenylmethoxy)phenyl]-2-phenylethanone;4-benzyloxy-2-hydroxydesoxybenzoin;Ethanone,1-[2-hydroxy-4-(phenylmethoxy)phenyl]-2-phenyl;1-(4-benzyloxy-2-hydroxyphenyl)-2-phenylethanone;4-benzyloxy-2-hydroxyphenyl benzyl ketone;benzyl 4-benzyloxy-2-hydroxyphenyl ketone;2-hydroxy-4-benzyloxyphenyl benzyl ketone
• CAS NO: 39604-80-3
• Molecular Formula: C21H18O3
• Molecular Weight: 318.372
• Mol File: 39604-80-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 104–108°C
• CAS DataBase Reference: Ethanone, 1-[2-hydroxy-4-(phenylmethoxy)phenyl]-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[2-hydroxy-4-(phenylmethoxy)phenyl]-2-phenyl-(39604-80-3)
• EPA Substance Registry System: Ethanone, 1-[2-hydroxy-4-(phenylmethoxy)phenyl]-2-phenyl-(39604-80-3)

Safety Data

• Hazardous Substances Data: 39604-80-3(Hazardous Substances Data)

Usage

Preparation

Preparation by partial benzylation of 2,4-dihydroxy-phenyl benzyl ketone, ? with benzyl chloride in the presence of potassium carbonate in refluxing acetone; ? with benzyl bromide in the presence of potassium carbonate in refluxing acetone or in the presence of potassium hydroxide at r.t. for 24 h (29%).

Upstream product

• 108-46-3 recorcinol 
• 103-80-0 phenylacetyl chloride 
• 3669-41-8 1-(2,4-dihydroxyphenyl)-2-phenylethanone 
• 100-51-6 benzyl alcohol 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 

Downstream Products

• 1042688-53-8 7-benzyloxy-3-hydroxymethyl-3-phenyl-2,3-dihydro-4H-1-benzopyran-4-one 
• 1621-56-3 7-methoxyisoflavone 
• 13057-72-2 7-hydroxyisoflavone 
• 746640-19-7 7-hydroxy-3-phenyl-2-[(pyridin-4-ylmethyl)thio]-4H-1-benzopyran-4-one 
• 869801-08-1 7-(biphenyl-4-ylmethoxy)-3-phenyl-2-(pyridin-4-ylmethylsulfanyl)-chromen-4-one 
• 869801-00-3 7-(naphthalen-2-ylmethoxy)-3-phenyl-2-(pyridin-4-ylmethylsulfanyl)-chromen-4-one 
• 869800-99-7 7-(naphthalen-1-ylmethoxy)-3-phenyl-2-(pyridin-4-ylmethylsulfanyl)-chromen-4-one 
• 746640-15-3 3-phenyl-7-(phenylmethoxy)-2-[(pyridin-4-ylmethyl)thio]-4H-1-benzopyran-4-one 
• 4253-05-8 7-benzyloxy-3-phenyl-chromen-4-one 

Relevant articles and documents

Biocatalytic acylation studies on novel 3-aryl-3-hydroxymethyl-2, 3-dihydro-4H-1-benzopyran-4-ones

(±)-3-Aryl-3-hydroxymethy1-2,3-dihydro-4H-1-benzopyran-4-ones have been synthesized in four steps starting with the coupling of resorcinol with corresponding phenylacetic acid leading to the formation of 2,4-dihydroxyphenyl aryl ketones, which upon monome

Lead optimization of 7-benzyloxy 2-(4′-pyridylmethyl)thio isoflavone aromatase inhibitors

Aromatase, the enzyme responsible for estrogen biosynthesis, is a particularly attractive target in the treatment of hormone-dependent breast cancer. The synthesis and biological evaluation of a series of 2-(4′-pyridylmethyl)thio, 7-alkyl- or aryl-substit

Synthese von 4-Alkoxy-2-hydroxyphenylketoximen als Metallextraktions-Reagenzien

The C-Acylation (Friedel-Crafts reaction) of resorcinol with aluminium chloride, the monoetherification in 4-position of the resulting 2,4-dihydroxyphenylketones, and the preparation of oximes (8, 9, 10, 11) from this ketones were investigated.The compounds obtained are characterized by elemental analysis, and the i.r., u.v. and 1H-n.m.r. spectra are discussed.Solubility data of some oximes are determined in water, octane and toluene.The extraction properties for copper-(II)-and iron-(III)-ions are measured by isotope methods in relation to the extragent structure, the extraction time and the pH-range.