39652-50-1Relevant articles and documents
Molecular recognition of α,β-unsaturated carbonyl compounds using aluminum tris(2,6-diphenylphenoxide) (ATPH): Structural and conformational analysis of ATPH complexes and application to the selective vinylogous aldol reaction
Saito, Susumu,Nagahara, Takashi,Shiozawa, Masahito,Nakadai, Masakazu,Yamamoto, Hisashi
, p. 6200 - 6210 (2007/10/03)
Various α,β-unsaturated carbonyl compounds were coordinated with aluminum tris(2,6-diphenylphenoxide) (ATPH) to give the corresponding Lewis acid-base complexes in a distinctive coordination fashion (selective coordination). ATPH recognizes carbonyl substrates and subsequently orients itself as it forms a stable complex through selective coordination with the carbonyl oxygen. Selective coordination also confers a conformational preference to each carbonyl compound under the steric and electronic influence of ATPH, which enables the vinylogous aldol reaction of α,β-unsaturated carbonyl compounds to give the corresponding γ-aldol products with different regio- and stereoselectivities.
Molecular recognition of carbonyl compounds using aluminum tris(2,6-diphenylphenoxide) (ATPH): New regio- and stereoselective alkylation of α,β-unsaturated carbonyl compounds [19]
Saito, Susumu,Shiozawa, Masahito,Nagahara, Takashi,Nakadai, Masakazu,Yamamoto, Hisashi
, p. 7847 - 7848 (2007/10/03)
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REGIOSELECTIVE CONTROL OF ALLYL ANIONS WITH CADMIUM CHLORIDE: α vs. γ CONDENSATION WITH ALDEHYDES
Bo, Lei,Fallis, Alex G.
, p. 5193 - 5196 (2007/10/02)
A general method for directing the condensation of allyl anions such as 2 with aldehydes preferentially to the γ position of the unsaturated nucleophile is described.The procedure employs cadmium chloride to control the regioselectivity and will facilitat
