39672-01-0Relevant articles and documents
A Complementary Process to Pauson-Khand-Type Annulation Reactions for the Construction of Fully Substituted Cyclopentenones
Millham, Adam B.,Kier, Matthew J.,Leon, Robert M.,Karmakar, Rajdip,Stempel, Zachary D.,Micalizio, Glenn C.
, p. 567 - 570 (2019)
A complementary process to the Pauson-Khand annulation is described that is well suited to forging densely substituted/oxygenated cyclopentenone products (including fully substituted variants). The reaction is thought to proceed through a sequence of meta
Tertiary Enamide-Triggered SEAr: Domino Allylation and Enamine-Type Addition
Beltran, Frédéric,Miesch, Laurence
supporting information, p. 1569 - 1573 (2019/03/12)
Two unprecedented domino reactions are described, starting from ketospiro-enesulfonamides. By treatment with ZrCl4 and allylsilane, an intramolecular electrophilic aromatic substitution and subsequent allylation is observed. By treatment with TiCl4 and allylsilane, a double enamine-type reaction takes place, thus creating simultaneously four contiguous stereogenic centers diastereoselectively.
Intramolecular reductive ketone-alkynoate coupling reaction promoted by (η2-propene)titanium
Schaefer, Christian,Miesch, Michel,Miesch, Laurence
supporting information; scheme or table, p. 3253 - 3257 (2012/06/01)
Intramolecular reductive coupling of cycloalkanones tethered to alkynoates in the presence of (η2-propene)titanium was successfully performed to provide hydroxy-esters in a diastereoselective manner. Subsequent lactonization afforded angularly
