397247-85-7

Basic information

• Product Name: 4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine
• Synonyms: 4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine
• CAS NO: 397247-85-7
• Molecular Weight: 368.416
• Mol File: 397247-85-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine(397247-85-7)
• EPA Substance Registry System: 4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine(397247-85-7)

Safety Data

• Hazardous Substances Data: 397247-85-7(Hazardous Substances Data)

Upstream product

• 397247-84-6 9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 
• 397247-79-9 6,7-dihydro-6-(2,3,5,6-tetrahydropyran-2-yl)oxy-4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 
• 397247-67-5 4-methoxy-2-[2-phthalimido-1-(2,3,5,6-tetrahydropyran-2-yl)oxyethyl]-7-azaindole 
• 397247-65-3 2-(1-hydroxy-2-phthalimidoethyl)-4-methoxy-7-azaindole 
• 397247-69-7 2-[2-amino-1-(2,3,5,6-tetrahydropyran-2-yl)oxyethyl]-4-methoxy-7-azaindole 
• 122379-63-9 4-methoxy-1H-pyrrolo<2,3-b>pyridine 
• 397247-82-4 6,7-dihydro-6-hydroxy-4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 

Downstream Products

• 397247-90-4 5-(2-aminopyrimidin-4-yl)-4-hydroxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 
• 397247-89-1 5-(2-acetylaminopyrimidin-4-yl)-4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 
• 397247-88-0 5-iodo-4-methoxy-9-tosylaminopyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine 

Relevant articles and documents

Derivatives of variolin b

The invention provides antitumour compounds of formula (I), wherein R1 is an aromatic substituent; R2 is hydrogen or a substituent when the dotted line is absent, or R2 is absent when the dotted line represents a bond to give a double bond between the nitrogen which bears R2 and the carbon which bears R3; R3 is an oxo group ═O when the dotted line is absent or is a substituent when the dotted line represents a bond to give a double bond between the nitrogen bearing R2 and the carbon bearing R3; R4 is hydrogen or a substituent; and pharmaceutically acceptable salts thereof.

Synthesis of variolin B

The total synthesis of variolin B from 4-methoxy-7-azaindole is described. The preparation of the protected amino derivative 10 and a coupling reaction of the iodo derivative 12 with 2-acetylamino-4-trimethylstannylpyrimidine are the key steps of the sequ