397275-27-3

Basic information

• Product Name: Benzonitrile, 4-[(1-cyclobutyl-4-piperidinyl)oxy]-
• CAS NO: 397275-27-3
• Molecular Formula: C16H20N2O
• Molecular Weight: 256.348
• Mol File: 397275-27-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4-[(1-cyclobutyl-4-piperidinyl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4-[(1-cyclobutyl-4-piperidinyl)oxy]-(397275-27-3)
• EPA Substance Registry System: Benzonitrile, 4-[(1-cyclobutyl-4-piperidinyl)oxy]-(397275-27-3)

Safety Data

• Hazardous Substances Data: 397275-27-3(Hazardous Substances Data)

Upstream product

• 685565-26-8 4-(4-piperidinyloxy)benzonitrile trifluoroacetate 
• 1191-95-3 cyclobutanone 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 1194-02-1 4-fluorobenzonitrile 
• 333954-86-2 4-(4-cyano phenoxy)piperidine-1-carboxylic acid tert-butyl ester 
• 118811-07-7 tert-butyl 4-(tosyloxy)piperidin-1-carboxylate 
• 767-00-0 4-cyanophenol 
• 224178-67-0 4-[(piperidin-4-yl)oxy]benzonitrile 

Downstream Products

• 685565-27-9 4-[(1-cyclobutyl-4-piperidinyl)oxy]benzoic acid hydrochloride 
• 1394808-23-1 N-[4-(1-cyclobutylpiperidin-4-yloxy)benzyl]morpholine-4-ylamide 
• 1394808-77-5 4-(1-cyclobutyl piperidin-4-yloxy)benzylamine 
• 769119-29-1 4-((1-cyclobutylpiperidin-4-yl)oxy)benzoic acid 
• 1087161-30-5 methyl 4-((1-cyclobutylpiperidin-4-yl)oxy)benzoate 
• 870997-68-5 4-((1-cyclobutylpiperidin-4-yl)oxy)benzaldehyde 
• 685565-68-8 N-{4-[(1-cyclobutyl-4-piperidinyl)oxy]benzoyl}isoindoline 
• 685565-69-9 N-{4-[(1-cyclobutyl-4-piperidinyl)oxy]benzoyl}-5-fluoroisoindoline 
• 685565-28-0 4-[(1-cyclobutyl-4-piperidinyl)oxy]benzoyl chloride hydrochloride 

Relevant articles and documents

MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS

The present invention relates to compounds compound according to Formula (III); and pharmaceutically acceptable salts, hydrates and solvates thereof. These compounds have D2receptor antagonist/(partial) agonist effects and H3antagonistic effects, pharmaceutical compositions thereof, and methods of using them for application in the prophylaxis or treatment of CNS disorders.

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The present invention relates to novel compounds of formula (I), and their pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their pha

ARYLOXYALKYLAMINE DERIVATES AS H3 RECEPTOR LIGANDS

The present invention relates to novel benzyloxy derivatives having pharmacological activity, processes for their preparation, to compositions containing them and to their use in the treatment of neurological and psychiatric disorders.