39755-15-2

Basic information

• Product Name: 8-OXO-8-PHENYLOCTANENITRILE
• Synonyms: 8-OXO-8-PHENYLOCTANENITRILE
• CAS NO: 39755-15-2
• Molecular Formula: C₁₄H₁₇NO
• Molecular Weight: 215.2909
• Mol File: 39755-15-2.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 384.761°C at 760 mmHg
• Flash Point: 186.497°C
• Appearance: /
• Density: 1.009g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.512
• CAS DataBase Reference: 8-OXO-8-PHENYLOCTANENITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 8-OXO-8-PHENYLOCTANENITRILE(39755-15-2)
• EPA Substance Registry System: 8-OXO-8-PHENYLOCTANENITRILE(39755-15-2)

Safety Data

• Hazardous Substances Data: 39755-15-2(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Synthetic Communications, 25, p. 101, 1995 DOI: 10.1080/00397919508010794

InChI:InChI=1/C14H17NO/c15-12-8-3-1-2-7-11-14(16)13-9-5-4-6-10-13/h4-6,9-10H,1-3,7-8,11H2

Upstream product

• 20965-27-9 7-bromo-heptanonitrile 
• 98-88-4 benzoyl chloride 
• 137407-47-7 (E)-1-phenylcyclooctene 
• 25328-90-9 1-phenylcyclooct-1-ene 
• 98-86-2 acetophenone 
• 98-83-9 isopropenylbenzene 
• 629-40-3 octanedinitrile 
• 98-80-6 phenylboronic acid 
• 7677-24-9 trimethylsilyl cyanide 
• 37908-41-1 1-hydroperoxy-1-phenylcycloheptane 
• 2082-21-5 1-phenylcycloheptanol 

Relevant articles and documents

In-situ-generation of alkylsilyl peroxides from alkyl hydroperoxides and their subsequent copper-catalyzed functionalization with organosilicon compounds

Alkylsilyl peroxides were generated in situ from the corresponding alkyl hydroperoxides using organosilicon compounds of the type Me3SiX (X = CN, N3, and halogens) and an amine base. Subsequent in situ copper-catalyzed homolytic cleavage of the alkylsilyl peroxides afforded alkyl radicals, which were then trapped with X (X = CN, N3, and halogens) to furnish products with new carbon-carbon, carbon-nitrogen, or carbon-halogen bonds in good to high yields.

Syntheses of Pyrroles, Pyridines, and Ketonitriles via Catalytic Carbopalladation of Dinitriles

The first example of the Pd-catalyzed addition of organoboron reagents to dinitriles, as an efficient means of preparing 2,5-diarylpyrroles and 2,6-diarylpyridines, has been discussed here. Furthermore, the highly selective carbopalladation of dinitriles with organoboron reagents to give long-chain ketonitriles has been developed as well. Based on the broad scope of substrates, excellent functional group tolerance, and use of commercially available substrates, the Pd-catalyzed addition reaction of arylboronic acid and dinitriles is expected to be significant in future synthetic procedures.

TEMPO-catalyzed aerobic oxygenation and nitrogenation of olefins via C=C double-bond cleavage

A novel TEMPO-catalyzed aerobic oxygenation and nitrogenation of hydrocarbons via C=C double-bond cleavage has been disclosed. The reaction employs molecular oxygen as the terminal oxidant and oxygen-atom source by metal-free catalysis under mild conditions. This method can be used for the preparation of industrially and pharmaceutically important N- and O-containing motifs, directly from simple and readily available hydrocarbons.