39760-56-0 Usage
Description
(E)-4-(DIETHOXY-PHOSPHORYL)-3-METHYL-BUT-2-ENOIC ACID ETHYL ESTER, also known as Triethyl (2E)-3-Methyl-4-phosphonocrotonate (CAS# 39760-56-0), is an organic compound with a unique chemical structure that features a diethoxy-phosphoryl group and a 3-methyl-but-2-enoic acid ethyl ester moiety. (E)-4-(DIETHOXY-PHOSPHORYL)-3-METHYL-BUT-2-ENOIC ACID ETHYL ESTER is known for its potential applications in various fields due to its distinct chemical properties.
Uses
Used in Organic Synthesis:
(E)-4-(DIETHOXY-PHOSPHORYL)-3-METHYL-BUT-2-ENOIC ACID ETHYL ESTER is used as a synthetic intermediate for the development of various organic compounds. Its unique structure allows it to be a valuable building block in the synthesis of complex molecules, particularly in the pharmaceutical and chemical industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (E)-4-(DIETHOXY-PHOSPHORYL)-3-METHYL-BUT-2-ENOIC ACID ETHYL ESTER is used as a key component in the development of new drugs. Its specific functional groups can be exploited to create novel therapeutic agents with potential applications in treating various diseases and medical conditions.
Used in Chemical Research:
(E)-4-(DIETHOXY-PHOSPHORYL)-3-METHYL-BUT-2-ENOIC ACID ETHYL ESTER is also utilized in chemical research as a model compound to study various reaction mechanisms and to develop new synthetic methodologies. Its reactivity and structural features make it an interesting subject for academic and industrial research.
Check Digit Verification of cas no
The CAS Registry Mumber 39760-56-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,7,6 and 0 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 39760-56:
(7*3)+(6*9)+(5*7)+(4*6)+(3*0)+(2*5)+(1*6)=150
150 % 10 = 0
So 39760-56-0 is a valid CAS Registry Number.
39760-56-0Relevant articles and documents
Conformationally Defined Rexinoids and Their Efficacy in the Prevention of Mammary Cancers
Atigadda, Venkatram R.,Xia, Gang,Deshpande, Anil,Wu, Lizhi,Kedishvili, Natalia,Smith, Craig D.,Krontiras, Helen,Bland, Kirby I.,Grubbs, Clinton J.,Brouillette, Wayne J.,Muccio, Donald D.
, p. 7763 - 7774 (2015/10/20)
(2E,4E,6Z,8Z)-8-(3′,4′-Dihydro-1′(2H)-naphthalen-1′-ylidene)-3,7-dimethyl-2,3,6-octatrienoinic acid (UAB30) is currently undergoing clinical evaluation as a novel cancer prevention agent. In efforts to develop even more highly potent rexinoids that prevent breast cancer without toxicity, we further explore here the structure-activity relationship of two separate classes of rexinoids. UAB30 belongs to the class II rexinoids and possesses a 9Z-tetraenoic acid chain bonded to a tetralone ring, whereas the class I rexinoids contain the same 9Z-tetraenoic acid chain bonded to a disubstituted cyclohexenyl ring. Among the 12 class I and class II rexinoids evaluated, the class I rexinoid 11 is most effective in preventing breast cancers in an in vivo rat model alone or in combination with tamoxifen. Rexinoid 11 also reduces the size of established tumors and exhibits a therapeutic effect. However, 11 induces hypertriglyceridemia at its effective dose. On the other hand rexinoid 10 does not increase triglyceride levels while being effective in the in vivo chemoprevention assay. X-ray studies of four rexinoids bound to the ligand binding domain of the retinoid X receptor reveal key structural aspects that enhance potency as well as those that enhance the synthesis of lipids.
STEREOCHEMISTRY OF THE HORNER-EMMONS REACTION OF 3-FUNCTIONALIZED 2-METHYL-2-PROPENYLPHOSPHONATES WITH ALIPHATIC ALDEHYDES. 1. EFFECT OF SIZE OF THE ALKOXY GROUP ATTACHED TO THE PHOSPHORUS ATOM
Kryshtal', G. V.,Serebryakov, E. P.,Suslova, L. M.,Yanovskaya, L. A.
, p. 2142 - 2146 (2007/10/02)
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