397869-22-6

Basic information

• Product Name: 2-[(4-acetylphenylaminoacetyl)thiomethyl]benzimidazole
• Synonyms: 2-[(4-acetylphenylaminoacetyl)thiomethyl]benzimidazole
• CAS NO: 397869-22-6
• Molecular Weight: 339.418
• Mol File: 397869-22-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(4-acetylphenylaminoacetyl)thiomethyl]benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(4-acetylphenylaminoacetyl)thiomethyl]benzimidazole(397869-22-6)
• EPA Substance Registry System: 2-[(4-acetylphenylaminoacetyl)thiomethyl]benzimidazole(397869-22-6)

Safety Data

• Hazardous Substances Data: 397869-22-6(Hazardous Substances Data)

Upstream product

• 4344-85-8 (1H-benzimidazol-2-yl)methanethiol 
• 38283-38-4 4-(2-chloroacetamido)acetophenone 

Downstream Products

• 397869-25-9 2-(1H-benzoimidazol-2-ylmethylsulfanyl)-N-{4-[3-(4-bromo-phenyl)-acryloyl]-phenyl}-acetamide 
• 397869-27-1 2-(1H-benzoimidazol-2-ylmethylsulfanyl)-N-{4-[3-(4-dimethylamino-phenyl)-acryloyl]-phenyl}-acetamide 
• 397869-26-0 2-(1H-benzoimidazol-2-ylmethylsulfanyl)-N-{4-[3-(4-methoxy-phenyl)-acryloyl]-phenyl}-acetamide 
• 397869-23-7 2-(1H-benzoimidazol-2-ylmethylsulfanyl)-N-[4-(3-phenyl-acryloyl)-phenyl]-acetamide 
• 397869-24-8 2-(1H-benzoimidazol-2-ylmethylsulfanyl)-N-{4-[3-(4-chloro-phenyl)-acryloyl]-phenyl}-acetamide 

Relevant articles and documents

Synthesis and antimicrobial activity of novel pyrazole, pyrazoline, pyrazolinone and pyrazolidinedione derivatives of benzimidazole

Four novel series of pyrazolylbenzimidazole derivatives have been prepared, namely 2-[(1-substituted phenyl-3,5-dimethyl-4-pyrazolyl) methyl]benzimidazole 5a-d 2-[(1-substituted phenyl-3-methyl-5-oxo-4,5-dihydro-4-pyrazolyl-4-yl)methyl]benzimidazoles 6a-d; 2-[(1-substituted phenyl-3,5-dioxopyrazolidin-4-yl)methyl]benzimidazoles 7a-d and 2-{[4-(1-phenyl-5-aryl-4,5-dihydro-3-pyrazolyl) phenylaminoacetyl]thio-methyl}-benzimidazoles 12a-e. The antimicrobial testing of the prepared compounds was performed using Escherichia Coli (NCTC 5933) as Gram-negative bacteria, Staphylococcus aureus (NCTC 4163) as gram-positive bacteria and Candida albicans (NCTC 5310) as yeast like fungi. The most potent compound was the pyrazolone 6a which exhibits interesting antibacterial activity against the gram-negative bacteria E. coli.