39807-75-5

Basic information

• Product Name: 2-Propenenitrile, 3-(4-hydroxyphenyl)-2-(phenylsulfonyl)-
• CAS NO: 39807-75-5
• Molecular Formula: C15H11NO3S
• Molecular Weight: 285.323
• Mol File: 39807-75-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Propenenitrile, 3-(4-hydroxyphenyl)-2-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenenitrile, 3-(4-hydroxyphenyl)-2-(phenylsulfonyl)-(39807-75-5)
• EPA Substance Registry System: 2-Propenenitrile, 3-(4-hydroxyphenyl)-2-(phenylsulfonyl)-(39807-75-5)

Safety Data

• Hazardous Substances Data: 39807-75-5(Hazardous Substances Data)

Upstream product

• 873-55-2 sodium benzenesulfonate 
• 123-08-0 4-hydroxy-benzaldehyde 
• 107-14-2 chloroacetonitrile 
• 7605-28-9 2-(phenylsulfonyl)acetonitrile 

Downstream Products

• 39807-61-9 4-(4'-hydroxyphenyl)-1H-1,2,3-triazole-5-carbonitrile 

Relevant articles and documents

One-step synthesis of α,β-unsaturated arylsulfones by a novel multicomponent reaction of aromatic aldehydes, chloroacetonitrile, benzenesulfinic acid sodium salt

A new and green method for the synthesis of α,β-unsaturated arylsulfones had been achieved through the condensation of aromatic aldehydes, chloroacetonitrile, benzenesulfinic acid sodium salt in the presence of 1-butyl-3-methyl imidazolium hydroxide ([bmim]OH) in EtOH under reflux. The ionic liquid was recovered and recycled for subsequent reactions. The advantages of this protocol were non-toxic, easy work-up and good yields.

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Novel ligands for the HisB10 Zn2+ sites of the R-state insulin hexamer that are capable of prolonging the action of insulin preparations are disclosed.