398136-94-2

Basic information

• Product Name: 1H-Indole-1-acetic acid, 3-[[[3-cyano-4-(4-hydroxy-1-piperidinyl)phenyl]amino]carbonyl]-5-fluoro- 2-methyl-
• CAS NO: 398136-94-2
• Molecular Formula: C24H23FN4O4
• Molecular Weight: 450.469
• Mol File: 398136-94-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Indole-1-acetic acid, 3-[[[3-cyano-4-(4-hydroxy-1-piperidinyl)phenyl]amino]carbonyl]-5-fluoro- 2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-1-acetic acid, 3-[[[3-cyano-4-(4-hydroxy-1-piperidinyl)phenyl]amino]carbonyl]-5-fluoro- 2-methyl-(398136-94-2)
• EPA Substance Registry System: 1H-Indole-1-acetic acid, 3-[[[3-cyano-4-(4-hydroxy-1-piperidinyl)phenyl]amino]carbonyl]-5-fluoro- 2-methyl-(398136-94-2)

Safety Data

• Hazardous Substances Data: 398136-94-2(Hazardous Substances Data)

Upstream product

• 288251-78-5 5-amino-2-(4-hydroxypiperidin-1-yl)benzonitrile 
• 40258-78-4 1-bromoethyl acetate 

Relevant articles and documents

Fused bicyclic amide compounds and medicinal use thereof

The present invention provides a compound represented by the formula (I) wherein ring A is benzene, cyclohexane, pyridine, piperidine or a derivative thereof, imidazole or a derivative thereof and the like, ring B is benzene, cyclohexane, pyrrole or a derivative thereof, furan, thiophene and the like, R1, R2 and R3 are each hydrogen, alkyl, halogen, hydroxyl group, alkoxy and the like, W is hydrogen, alkyl or hydroxycarbonylalkyl, X is halogen, cyano, nitro and the like, X′ is hydrogen, halogen and the like, and Y is alkyl, hydroxyalkyl, hydroxycarbonylalkyl, aminoalkyl and the like, a salt thereof, and a pharmaceutical agent containing the compound. The compound of the present invention shows a superior inhibitory effect on the proliferation of activated lymphocyte and is useful as an agent for the prophylaxis or treatment of various autoimmune diseases.