39897-13-7 Usage
Description
(S)-N-(p-toluenesulfonyl)azetidine-2-carboxylic acid is a chemical compound that belongs to the class of azetidine carboxylic acids. It is characterized by a chiral center and a sulfonyl group attached to the nitrogen atom, which contributes to its reactivity and stability in various chemical reactions. This versatile compound is widely used in organic synthesis and pharmaceutical research, serving as a starting material for the preparation of diverse drugs and biologically active molecules. The presence of the azetidine ring and carboxylic acid functionality allows for the creation of unique molecular scaffolds with potential pharmacological properties, making it a valuable asset in both academic and industrial chemistry.
Uses
Used in Pharmaceutical Research:
(S)-N-(p-toluenesulfonyl)azetidine-2-carboxylic acid is used as a starting material for the synthesis of various drugs and biologically active molecules. Its unique structure and functional groups enable the development of new compounds with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-N-(p-toluenesulfonyl)azetidine-2-carboxylic acid is used as a building block for creating complex molecular structures. The sulfonyl group enhances the reactivity of the molecule, allowing for a wide range of chemical reactions and the formation of diverse molecular scaffolds.
Used in Academic Chemistry:
(S)-N-(p-toluenesulfonyl)azetidine-2-carboxylic acid is utilized in academic research to explore its potential applications and to study the effects of its unique structure on chemical reactions and molecular interactions.
Used in Industrial Chemistry:
In the industrial chemistry sector, (S)-N-(p-toluenesulfonyl)azetidine-2-carboxylic acid is employed as a key intermediate in the production of various pharmaceuticals and other chemical products. Its versatility and stability make it a valuable component in the synthesis of a wide range of compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 39897-13-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,8,9 and 7 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 39897-13:
(7*3)+(6*9)+(5*8)+(4*9)+(3*7)+(2*1)+(1*3)=177
177 % 10 = 7
So 39897-13-7 is a valid CAS Registry Number.
39897-13-7Relevant articles and documents
Inexpensive multigram-scale synthesis of cyclic enamines and 3-N spirocyclopropyl systems
Kumar, Pratik,Zainul, Omar,Laughlin, Scott T.
supporting information, p. 652 - 656 (2018/02/07)
Cyclic enamines are important synthons for many synthetic and pharmacological targets. Here, we report an inexpensive, catalyst-free, multigram-scale synthesis for cyclic enamines with exocyclic double bonds and four- to seven-membered rings. This strategy is more conducive to scale up, permissive of functionalization around the cyclic system, and less sensitive to the nature of the N-protecting group than previously-described methods for cyclic enamine synthesis. Further, we explore application of these enamines to the synthesis of highly-strained spirocyclic 3N-cyclopropyl scaffolds.
Enantiodivergent synthesis of N-protected azetidine-2-carboxylic acid
Biswas, Tanmoy,Mukherjee, Jyoti Prasad,Chattopadhyay, Shital K.
, p. 1416 - 1422,7 (2020/09/16)
A new route to both enantiomers of N-tosyl-azetidine-2- carboxylic acid has been developed from (R)-2-cyclohexylideneglyceraldehyde which proceeded with good overall yield and excellent enantiomeric purity.
Thermal Arndt-Eistert reactions of N-tosyl cyclic α-amino acids
Jin, Jing Yi,Wu, Xue,Tian, Guan Rong
, p. 2535 - 2541 (2007/10/03)
Thermal Arndt-Eistert reactions of N-tosyl cyclic α-amino acids were studied to explore the preparation of α,β-unsaturated esters bearing a terminal tosylamino group. For L-N-tosyl-aziridine 2-carboxylic acid and L-N-tosyl-azetidine 2-carboxylic acid, the corresponding (E)-α,β- unsaturated esters were obtained stereospecifically. Copyright Taylor & Francis, Inc.
