399-45-1 Usage
Description
(2-fluoro-4-nitrophenoxy)acetic acid is a chemical compound with the molecular formula C8H6FNO5. It is a derivative of acetic acid, with a 2-fluoro-4-nitrophenyl group attached to the carboxylic acid group. (2-fluoro-4-nitrophenoxy)acetic acid is of interest due to the presence of both a fluoro and a nitro group in its structure, which can impact biological activity and pesticide efficacy.
Uses
Used in Pharmaceutical Synthesis:
(2-fluoro-4-nitrophenoxy)acetic acid is used as a building block for the synthesis of pharmaceuticals. Its unique structure, featuring both fluoro and nitro groups, makes it a valuable component in the development of new drugs with enhanced biological activity.
Used in Agrochemical Development:
In the agrochemical industry, (2-fluoro-4-nitrophenoxy)acetic acid is used as a precursor for the synthesis of pesticides and other agricultural chemicals. The presence of fluoro and nitro groups can improve the efficacy of these compounds, making them more effective in controlling pests and diseases.
Used in Organic Chemistry Research:
(2-fluoro-4-nitrophenoxy)acetic acid is also utilized in organic chemistry research for the synthesis of various organic compounds. Its distinctive structure allows for the exploration of new chemical reactions and the creation of novel molecules with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 399-45-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,9 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 399-45:
(5*3)+(4*9)+(3*9)+(2*4)+(1*5)=91
91 % 10 = 1
So 399-45-1 is a valid CAS Registry Number.
399-45-1Relevant articles and documents
The anti-invasive role of novel synthesized pyridazine hydrazide appended phenoxy acetic acid against neoplastic development targeting matrix metallo proteases
Eissa Mohammed, Yasser Hussein,Thirusangu, Prabhu,Zabiulla,Vigneshwaran,B.T, Prabhakar,Khanum, Shaukath Ara
, p. 375 - 386 (2017/09/02)
Neoplastic metastasis is a major process where tumor cells migrate from the primary tumor and colonize at other parts of our body to form secondary tumor. Cancer incidences are rising and novel anti-neoplastic compounds with new mechanism of actions are essential for preventing cancer related deaths. In the current examination, a novel series of pyridazine analogues 6a-l was synthesized and evaluated against metastatic neoplastic cells. Experimental data postulated compound 6j has potential cytotoxic efficacy with prolonged activity against various cancer cells, including A549, HepG2, A498, CaSki and SiHa cells. Moreover, compound 6j arrests the A549 migration and invasions markedly by counteracting matrix metalloproteinase (MMP)-2 and MMP-9 expressions. Also, compound 6j proved its potentiality against Dalton's solid lymphoma progression in-vivo by abridging MVD and MMP expressions. Compound 6j interacts with MMP-2 and MMP-9 by H- bond in-silico, thereby down regulates the MMPs action in tumourigenesis. Altogether, we concluded that compound 6j down regulates MMP-2 and MMP-9 and thereby impairs metastatic cancer cell migration and invasions which can be translated into a potent anti-neoplastic agent.