39931-88-9Relevant articles and documents
Novel phosphorus-containing 17β-side chain mifepristone analogues as progesterone receptor antagonists
Jiang, Weiqin,Allan, George,Chen, Xin,Fiordeliso, James J.,Linton, Olivia,Tannenbaum, Pamela,Xu, Jun,Zhu, Peifang,Gunnet, Joseph,Demarest, Keith,Lundeen, Scott,Sui, Zhihua
, p. 949 - 954 (2006)
A novel series of steroidal compounds were designed and synthesized with various phosphorus-containing groups on the 17β-side chain as progesterone receptor antagonists. The structure-activity relationships of these compounds are discussed. Selected compo
Design and synthesis of fluorescently labeled steroidal antiestrogens
Hanson, Robert N.,Gajadeera, Nisal
, p. 39 - 46 (2019/02/28)
A set of derivatives of 11β-(4-oxyphenyl)estradiol were prepared as potential fluorescent imaging agents for the evaluation of the estrogen receptor. The compounds were designed based on the established affinity and selectivity of 11β-[4-(dimethylethoxy)p
First synthesis and characterization for the stereoisomers of Ulipristal acetate
Zhao, Yi,Li, Xiaolong,Liu, Hong,Yu, Yongguo,Hai, Li,Guo, Li,Wu, Yong
, p. 7 - 16 (2015/01/30)
The three stereoisomers, 11α,17α-isomer I, 11α,17β-isomer II and 11β,17β-isomer III are related substances of the selective progesterone receptor modulator Ulipristal acetate. Herein, we presented an efficient and practical synthesis approach to deliver t