39996-22-0

Basic information

• Product Name: (2-AMINO-4,5-DIMETHOXY-PHENYL)-PHENYL-METHANONE
• Synonyms: (2-AMINO-4,5-DIMETHOXY-PHENYL)-PHENYL-METHANONE
• CAS NO: 39996-22-0
• Molecular Formula: C₁₅H₁₅NO₃
• Molecular Weight: 257.28
• Mol File: 39996-22-0.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 461.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.181±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 0.99±0.13(Predicted)
• CAS DataBase Reference: (2-AMINO-4,5-DIMETHOXY-PHENYL)-PHENYL-METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (2-AMINO-4,5-DIMETHOXY-PHENYL)-PHENYL-METHANONE(39996-22-0)
• EPA Substance Registry System: (2-AMINO-4,5-DIMETHOXY-PHENYL)-PHENYL-METHANONE(39996-22-0)

Safety Data

• Hazardous Substances Data: 39996-22-0(Hazardous Substances Data)

Usage

Description

(2-AMINO-4,5-DIMETHOXY-PHENYL)-PHENYL-METHANONE, also known as 2C-H, is a psychoactive phenethylamine that is structurally related to mescaline. It is classified as a hallucinogen and is known for its hallucinogenic and psychedelic effects, causing altered perception, mood, and thought processes. The substance is commonly ingested orally and can produce visual and auditory hallucinations, as well as altered feelings of time and space. However, it is considered to have a high potential for abuse and is illegal in most countries. Additionally, it is considered to have a high potential for causing harm to the user, both physically and psychologically.

Uses

Used in Research Applications:
(2-AMINO-4,5-DIMETHOXY-PHENYL)-PHENYL-METHANONE is used as a research chemical for studying the effects of hallucinogenic substances on the human brain and their potential therapeutic applications. Its structural similarity to mescaline allows researchers to investigate the mechanisms of action and potential benefits of these types of compounds.
Used in Pharmaceutical Development:
(2-AMINO-4,5-DIMETHOXY-PHENYL)-PHENYL-METHANONE is used as a starting point for the development of new pharmaceuticals that may have potential therapeutic applications. Its unique properties and effects on the human brain can provide valuable insights into the development of new treatments for various mental health conditions.
Used in Forensic Analysis:
(2-AMINO-4,5-DIMETHOXY-PHENYL)-PHENYL-METHANONE is used in forensic analysis to identify and analyze the presence of this substance in biological samples, such as blood or urine. This can be important in cases where the substance may have been involved in illegal activities or for determining the cause of death in cases of drug overdose.

Upstream product

• 108-86-1 bromobenzene 
• 26961-27-3 2-amino-4,5-dimethoxybenzonitrile 
• 926888-02-0 2-amino-4,5,N-trimethoxy-N-methylbenzamide 
• 255896-36-7 (4,5-dimethoxy-2-nitrophenyl)-(phenyl)methanone 
• 20197-92-6 6,7-dimethoxy-1H-benzo[d][1,3]oxazine-2,4-dione 
• 5653-40-7 2-Amino-4,5-dimethoxybenzoic acid 
• 91-16-7 1,2-dimethoxybenzene 
• 4038-14-6 3,4-dimethoxybenzophenone 
• 98-88-4 benzoyl chloride 
• 100-47-0 benzonitrile 
• 6315-89-5 3,4-dimethoxyaniline 
• 873-55-2 sodium benzenesulfonate 
• 98-80-6 phenylboronic acid 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 58487-55-1 4-phenyl-6,7-dimethoxyquinazoline 
• 477742-58-8 7,8-dimethoxy-5-phenyl-1,3-dihydrobenzo[e][1,4]diazepin-2-one 
• 314272-81-6 N-(2-benzoyl-4,5-dimethoxyphenyl)acetamide 
• 873984-49-7 2-benzoyl-4,5-dimethoxy-1-phenylcarboxamidobenzene 
• 924635-63-2 N-(2-benzoyl-4,5-dimethoxyphenyl)methanesulfonamide 
• 309927-64-8 2-benzoyl-4,5-dimethoxy-1-(4-methylphenylsulfonamido)benzene 
• 924279-57-2 3-amino-7,8-dimethoxy-5-phenyl-1,3-dihydrobenzo[e][1,4]diazepin-2-one 
• 926888-11-1 (7,8-dimethoxy-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)carbamic acid benzyl ester 
• 375833-72-0 N-[2-hydroxy(phenyl)methyl-4,5-dimethoxyphenyl]acetamide 
• 924635-64-3 N-[2-hydroxy(phenyl)methyl-4,5-dimethoxyphenyl]methanesulfonamide 
• 924635-65-4 2-hydroxy(phenyl)methyl-4,5-dimethoxy-1-phenylcarboxamidobenzene 
• 924635-66-5 N-{4,5-dimethoxy-2-[5-methyl-2-furyl(phenyl)methyl]phenyl}methanesulfonamide 
• 924635-68-7 N-{2-[5-(tert-butyl)-2-furyl(phenyl)methyl]-4,5-dimethoxyphenyl}acetamide 
• 924635-67-6 4,5-dimethoxy-2-[5-methyl-2-furyl(phenyl)methyl]-1-phenylcarboxamidobenzene 

Relevant articles and documents

Enantioselective Intramolecular Copper-Catalyzed Borylacylation

An enantioselective copper-catalyzed intramolecular borylacylation is reported. The reaction proceeds through an initial enantioselective borylcupration of the styrene, followed by a nucleophilic attack on the tethered carbamoyl chloride. The products, chiral borylated 3,3-disubstituted oxindoles, were generated in excellent yields and enantioselectivities. The versatile carbon–boron bond provides a platform for a wide array of diversification.

Palladium-catalyzed direct addition of arylboronic acids to 2-aminobenzonitrile derivatives: Synthesis, biological evaluation and in silico analysis of 2-aminobenzophenones, 7-benzoyl-2-oxoindolines, and 7-benzoylindoles

A palladium-catalyzed direct addition of arylboronic acids to unprotected 2-aminobenzonitriles has been developed, leading to a wide range of 2-aminobenzophenones with moderate to excellent yields. The transformation has broad scope and high functional group tolerance. Moreover, 2-oxoindoline-7-carbonitrile and indole-7-carbonitrile were applicable to this process for the construction of 7-benzoyl-2-oxoindolines and 7-benzoylindoles, respectively. Among the compounds examined, compound 4e possessed the most potent anticancer activity against H446 and HGC-27 in vitro, with IC50 values of 0.02 μmol L-1 and 0.09 μmol L-1, respectively, while compound 4a showed the best potent anticancer activity against SGC-7901 with an IC50 value of 0.01 μmol L-1. Furthermore, we also performed in silico molecular docking calculations to investigate the interaction mode and binding affinity between the examined compounds and their tubulin target. This journal is

Simple route to 3-(2-indolyl)-1-propanones via a furan recyclization reaction

A simple route to 1-R-3-(2-indolyl)-1-propanones has been elaborated based on recyclization of 2-(2-aminobenzyl)furan derivatives. Being a modification of the Reissert indole synthesis, our approach employs the furan ring as a source of carbonyl function. This approach is general and allows varying of substituents in aromatic ring as well as in 3-position of indole nucleus.