40003-15-4

Basic information

• Product Name: 5-Thiazolecarboxylic acid, 4-methyl-2-(phenylthio)-, ethyl ester
• CAS NO: 40003-15-4
• Molecular Formula: C13H13NO2S2
• Molecular Weight: 279.384
• Mol File: 40003-15-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-Thiazolecarboxylic acid, 4-methyl-2-(phenylthio)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Thiazolecarboxylic acid, 4-methyl-2-(phenylthio)-, ethyl ester(40003-15-4)
• EPA Substance Registry System: 5-Thiazolecarboxylic acid, 4-methyl-2-(phenylthio)-, ethyl ester(40003-15-4)

Safety Data

• Hazardous Substances Data: 40003-15-4(Hazardous Substances Data)

Upstream product

• 7238-62-2 ethyl 2-chloro-4-methylthiazole-5-carboxylate 
• 108-98-5 thiophenol 
• 7210-76-6 ethyl-2-amino-4-methylthiazole-5-carboxylate 
• 22900-83-0 ethyl 2-bromo-4-methyl-1,3-thiazole-5-carboxylate 

Downstream Products

• 477533-75-8 ethyl 4-methyl-2-phenylsulfanylthiazole-5-methanol 

Relevant articles and documents

NOVEL HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF

The novel heterocyclic compound of the present invention is a novel heterocyclic compound having the formula (I)R15―C(R14)=N-O― wherein R1 is H or C1-6 alkyl, R2 is H, -CO-C(R4)=C(R4)-R5 wherein R4 is H or C1-4 alkyl, and R5 is C4-8 alkyl, C2-8 alkenyl and the like, and the like, Y is the following group wherein X is O or S, R7 is the same as R4, R8 is R10-C(R9)=C(R9)- wherein R9 is the same as R4, R10 is C3-6 alkyl and the like, and the like, R14 is the same as R4, and R15 is aryl and the like, Y-(CH2)n-O- is bonded to the 6- or 7-position of the tetrahydroisoquinoline skeleton, and n is an integer of 1 to 4, or a pharmaceutically acceptable salt thereof. The compound (I) of the present invention is useful as a hypoglycemic agent, a hypolipidemic agent, an insulin resistance improver, a therapeutic agent of diabetes, a therapeutic agent of diabetic complications, a glucose tolerance improver, an anti-arteriosclerosis agent, an anti-obesity agent, an antiinflammatory agent, an agent for the prophylaxis or treatment of PPAR-mediated diseases or an agent for the prophylaxis or treatment of syndrome X.