40051-12-5 Usage
Chemical class
Phenothiazine derivatives
Substituent
10-(3-chloropropyl) on the phenothiazine core
Type of derivative
Sulphonamide derivative
Pharmacological properties
Potent
Therapeutic applications
Antipsychotic, antiemetic, and antihistaminic agent
Mechanism of action
Dopamine receptor antagonist
Investigated for
Treating neurological and psychiatric disorders
Antimicrobial activity
Significant
Antifungal activity
Significant
Research and development
Important chemical in medicinal chemistry field
Structure
Unique
Profile
Pharmacological
Further research
Potential for new therapeutic applications and drug development
Check Digit Verification of cas no
The CAS Registry Mumber 40051-12-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,0,5 and 1 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 40051-12:
(7*4)+(6*0)+(5*0)+(4*5)+(3*1)+(2*1)+(1*2)=55
55 % 10 = 5
So 40051-12-5 is a valid CAS Registry Number.
InChI:InChI=1/C17H19ClN2O2S2/c1-19(2)24(21,22)13-8-9-17-15(12-13)20(11-5-10-18)14-6-3-4-7-16(14)23-17/h3-4,6-9,12H,5,10-11H2,1-2H3
40051-12-5Relevant articles and documents
NOVEL COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES RELATED TO ACTIVATED LYMPHOCYTES
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Page/Page column 57-58, (2008/06/13)
The present invention relates to inhibiting proliferation and inducing apoptosis in activated lymphocytes, including T cells and B cells. The invention also provides compositions and methods for inhibiting proliferation and inducing apoptosis in activated lymphocytes, as well methods for treating diseases associated with activated lymphocytes by administering 5-HT receptor antagonists.
