40067-66-1

Basic information

• Product Name: 2-(TRIFLUOROMETHYL)BENZAMIDOXIME
• Synonyms: 2-(Trifluoromethyl)-N'-hydroxybenzamidine;2-Trifluoromethylbenzamidoxime; N'-Hydroxy-2-(trifluoromethyl)benzenecarboximidamide
• CAS NO: 40067-66-1
• Molecular Formula: C₈H₇F₃N₂O
• Molecular Weight: 204.15
• Mol File: 40067-66-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 312.9°Cat760mmHg
• Flash Point: 143°C
• Appearance: /
• Density: 1.4g/cm³
• CAS DataBase Reference: 2-(TRIFLUOROMETHYL)BENZAMIDOXIME(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(TRIFLUOROMETHYL)BENZAMIDOXIME(40067-66-1)
• EPA Substance Registry System: 2-(TRIFLUOROMETHYL)BENZAMIDOXIME(40067-66-1)

Safety Data

• Hazardous Substances Data: 40067-66-1(Hazardous Substances Data)

Usage

Structure

Benzene ring with a trifluoromethyl group attached to a nitrogen atom, and an oxime functional group

Type of compound

Organic compound

Uses

Building block in organic synthesis and pharmaceutical research for the production of various chemicals and drugs

Potential applications

Development of new pharmaceuticals and agrochemicals

Unique properties

Trifluoromethyl group imparts unique chemical and physical properties, useful in a range of applications in chemistry and biochemistry.

Upstream product

• 447-60-9 2-(trifluoromethyl)benzonitrile 
• 447-61-0 2-Trifluoromethylbenzaldehyde 
• 74467-00-8 N-[[2-(trifluoromethyl)phenyl]methylidene]hydroxylamine 

Downstream Products

• 131337-66-1 C₁₀H₈ClF₃N₂O₂ 
• 110704-47-7 3-(2-trifluoromethylphenyl)-5-chloromethyl-1,2,4-oxadiazole 
• 110721-48-7 3-[3-(2-Trifluoromethylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-4-oxo-3H-phthalazin-1-ylacetic acid 
• 110704-54-6 Ethyl 3-[3-(2-trifluoromethylphenyl)-1,2,4-oxadiazol-5-ylmethyl]-4-oxo-3H-phthalazin-1-ylacetate 
• 1352079-38-9 C₁₉H₂₂F₃N₃O₃ 
• 1332500-90-9 5-(5-chlorothiophen-2-yl)-4-(2-fluorobenzyl)-2-({3-[2-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-2,4-dihydro-3H-1,2,4-triazol-3-one 
• 343332-11-6 N-(2-(trifluoromethyl)phenyl)cianamide 

Relevant articles and documents

Design, synthesis, and biological evaluation of 1,2,4-oxadiazole-containing pyrazolo[3,4-b]pyridinones as a new series of AMPKɑ1β1γ1 activators

Adenosine monophosphate-activated protein kinase (AMPK) plays a key role in maintaining whole-body homeostasis and has been regarded as a therapeutic target for the treatment of diabetic nephropathy (DN). Herein, a series of 1,2,4-oxadiazole-containing py

1,2,4-Oxadiazole ring–containing pyridylpyrazole-4-carboxamides: Synthesis and evaluation as novel insecticides of the anthranilic diamide family

Herein, we describe the preparation of pyridylpyrazole-4-carboxamides containing a 1,2,4-oxadiazole ring as novel anthranilic diamide derivatives and compare their insecticidal activities to that of chlorantraniliprole, a well-established potent insectici

COMPOUNDS HAVING AN ETHR INHIBITING ACTIVITY - USE OF SAID COMPOUNDS AS DRUGS - PHARMACEUTICAL COMPOSITION AND PRODUCT CONTAINING SAID COMPOUNDS

The present invention relates to compounds of Formula (I), wherein R1 is chosen among the following radicals : (II); (III); (IV), (V), (VI) (VII) and n= 1 or 2 and m=1 or 2 with the proviso that m=2 when R1 is (VIII). The present invention also relates to the use thereof as drugs, more particularly in the treatment of mycobacterial infections and more particularly in the treatment of tuberculosis.