400877-05-6

Basic information

• Product Name: 4-Aminomethyl-1-methylpyrazole
• Synonyms: TIMTEC-BB SBB000039;AKOS PAO-0126;AKOS B000529;1-(1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE;C-(1-METHYL-1H-PYRAZOL-4-YL)-METHYLAMINE;ART-CHEM-BB B000529;(1-Methyl-1H-pyrazol-4-yl)methylamine;4-Aminomethyl-1-methylpyrazole
• CAS NO: 400877-05-6
• Molecular Formula: C₅H₉N₃
• Molecular Weight: 111.15
• Mol File: 400877-05-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 220 °C
• Flash Point: 87 °C
• Appearance: /
• Density: 1.16
• Vapor Pressure: 0.117mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.98±0.29(Predicted)
• CAS DataBase Reference: 4-Aminomethyl-1-methylpyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Aminomethyl-1-methylpyrazole(400877-05-6)
• EPA Substance Registry System: 4-Aminomethyl-1-methylpyrazole(400877-05-6)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 400877-05-6(Hazardous Substances Data)

Usage

General Description

4-Aminomethyl-1-methylpyrazole, also known as AMP, is a chemical compound with a molecular formula of C5H8N2. It is a heterocyclic organic compound with a pyrazole ring and an amino group attached to a methyl group. AMP is commonly used as a ligand in coordination chemistry and as a chelating agent in metal-ion transport. It is also used in the synthesis of various pharmaceutical compounds and as a reagent in organic chemistry reactions. Additionally, AMP has been studied for its potential application in the treatment of various diseases and as an inhibitor of specific enzymes. Overall, 4-Aminomethyl-1-methylpyrazole has a range of important industrial and research applications.

InChI:InChI=1/C5H9N3/c1-8-4-5(2-6)3-7-8/h3-4H,2,6H2,1H3

Upstream product

• 85290-80-8 ethyl 1-methylpyrazole-4-carboxylate 
• 89280-01-3 1 -methyl-1H-pyrazole-4-carboxamide 
• 43193-15-3 1-methyl-1H-pyrazole-4-carbaldehyde oxime 

Downstream Products

• 1065113-52-1 2-benzyl-4-[(1-methyl-1H-pyrazol-4-ylmethyl)amino]-5,6,8,9-tetrahydropyrimido[4,5-d]azepine-7-carboxylic acid ethyl ester 
• 675617-94-4 4-methyl-N-[(1-methyl-1H-pyrazol-4-yl)methyl]-6-[4-(methylsulfonyl)phenyl]-2-pyridinamine 
• 1383377-17-0 4-[3-(4-fluorophenyl)-1-methyl-1H-pyrazol-4-yl]-6-[(1-methyl-1H-pyrazol-4-yl)methyl]-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one 
• 1571134-09-2 C₂₇H₂₃F₃N₆O₂ 
• 1333674-47-7 C₁₇H₁₉N₃O₃ 
• 1282606-63-6 3-(1-(4-fluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-N-((1-methyl-1H-pyrazol-4-yl)methyl)-1H-pyrazole-5-carboxamide 
• 1072804-35-3 2-(1-(4-fluorobenzyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)-4-methyl-N-((1-methyl-1H-pyrazol-4-yl)methyl)thiazole-5-carboxamide 
• 1065110-52-2 (2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-yl)-(1-methyl-1H-pyrazol-4-ylmethyl)amine 

Relevant articles and documents

Efficient hydrogenation of benzaldoximes and Schiff bases on ceramic high-porosity palladium catalysts

An efficient catalytic method for the synthesis of benzyl- and dibenzylamines by hydrogenating oximes and Schiffbases was developed on palladium supported high-porosity foamed ceramic block catalyst. The multiple regeneration ability of the foamed ceramic block catalyst can significantly decrease the Pd consumption as compared to the use of the conventional 10%Pd/C catalyst. Owing to a high hardness of the foamed ceramic catalyst, the reaction mixture can rapidly be removed from the reactor without using filtering devices. The structures produced by the reaction are fragments of biologically active and natural molecules. Antiproliferative properties of dibenzylamines revealed on the sea urchin embryo model suggest that these compounds can be considered as promising agents for the design of new anticancer drugs.