40094-22-2 Usage
Description
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-8-bromo-2'-deoxy-N-[(dimethylamino)methylene]guanosine is a complex chemical compound with potential applications in medicinal chemistry. It is an 8-bromo-2'-deoxyguanosine derivative, featuring an N-[(dimethylamino)methylene] group at the 8-position and a 5'-O-[bis(4-methoxyphenyl)phenylmethyl] group at the 5'-position. 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-8-bromo-2'-deoxy-N-[(dimethylamino)methylene]guanosine exhibits structural similarities to nucleoside analogs that have shown antiviral and cytotoxic activities. The unique structure and functional groups of 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-8-bromo-2'-deoxy-N-[(dimethylamino)methylene]guanosine make it a promising candidate for further research and potential development as a pharmaceutical agent. Its properties make it of interest for investigating its potential as a therapeutic agent in the treatment of various diseases.
Uses
Used in Pharmaceutical Industry:
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-8-bromo-2'-deoxy-N-[(dimethylamino)methylene]guanosine is used as a potential therapeutic agent for the treatment of various diseases due to its structural similarities to nucleoside analogs with antiviral and cytotoxic activities.
Used in Antiviral Applications:
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-8-bromo-2'-deoxy-N-[(dimethylamino)methylene]guanosine is used as an antiviral agent, leveraging its structural similarities to nucleoside analogs that have demonstrated antiviral properties.
Used in Cytotoxic Applications:
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-8-bromo-2'-deoxy-N-[(dimethylamino)methylene]guanosine is used as a cytotoxic agent, owing to its potential to exhibit cytotoxic activities similar to other nucleoside analogs.
Used in Medicinal Chemistry Research:
5'-O-[bis(4-methoxyphenyl)phenylmethyl]-8-bromo-2'-deoxy-N-[(dimethylamino)methylene]guanosine is used as a research compound in medicinal chemistry for further investigation of its potential as a pharmaceutical agent and its therapeutic applications in treating various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 40094-22-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,0,9 and 4 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 40094-22:
(7*4)+(6*0)+(5*0)+(4*9)+(3*4)+(2*2)+(1*2)=82
82 % 10 = 2
So 40094-22-2 is a valid CAS Registry Number.
40094-22-2Relevant articles and documents
ION SENSOR DNA AND RNA SEQUENCING BY SYNTHESIS USING NUCLEOTIDE REVERSIBLE TERMINATORS
-
, (2017/07/15)
This disclosure is related to a method for determining the identity of a nucleotide residue of a single-stranded DNA or RNA, or sequencing DNA or RNA, in a solution using an ion-sensing field effect transistor and reversible nucleotide terminators.
H-phosphonate DNA synthesis without amino protection
Kung,Jones
, p. 5869 - 5872 (2007/10/02)
DNA synthesis by the H-phosphonate method does not require the use of amino protecting groups. The cytosine amino group, and the guanine O6/N1 positions, do react with the condensing agent to some extent, but these derivatives are cleaved under the standa
AUTOMATED CHLORIDITE AND AMIDITE SYNTHESIS OF OLIGODESOXYRIBONUCLEOTIDES ON A LONG CHAIN SUPPORT USING AMIDINE PROTECTED PURINE NUCLEOSIDES
Arnold, Lubos,Tocik, Zdenek,Bradkova, Eliska,Hostomsky, Zdenek,Paces, Vaclav,Smrt, Jiri
, p. 523 - 532 (2007/10/02)
Preparation of solid supports with long aliphatic spacer for the oligonucleotide synthesis is described.Automated synthesis of oligodeoxyribonucleotides using in situ prepared methylchlorophosphite intermediates from amidine protected purine nucleosides i