40101-22-2

Basic information

• Product Name: 1H-Isoindole-1,3(2H)-dione, 2-(3,4,5-trimethylphenyl)-
• CAS NO: 40101-22-2
• Molecular Formula: C17H15NO2
• Molecular Weight: 265.312
• Mol File: 40101-22-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Isoindole-1,3(2H)-dione, 2-(3,4,5-trimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Isoindole-1,3(2H)-dione, 2-(3,4,5-trimethylphenyl)-(40101-22-2)
• EPA Substance Registry System: 1H-Isoindole-1,3(2H)-dione, 2-(3,4,5-trimethylphenyl)-(40101-22-2)

Safety Data

• Hazardous Substances Data: 40101-22-2(Hazardous Substances Data)

Upstream product

• 136918-14-4 phthalimide 
• 526-73-8 1,2,3-trimethylbenzene 
• 85-44-9 phthalic anhydride 
• 1639-31-2 3,4,5-trimethylaniline 

Downstream Products

• 106747-39-1 2-[(1H-benzimidazol-2-yl)sulfinylmethyl]-3,4,5-trimethylbenzenamine 
• 114060-21-8 N-<2-(hydroxymethyl)-3,4,5-trimethylphenyl>phthalimide 

Relevant articles and documents

Sterically controlled, palladium-catalyzed intermolecular amination of arenes

We report the Pd-catalyzed amination of arenes to form N-aryl phthalimides with regioselectivity controlled predominantly by steric effects. Mono-, di-, and trisubstituted arenes lacking a directing group undergo amination reactions with moderate to high yields and high regioselectivities from sequential addition of PhI(OAc)2 as an oxidant in the presence of Pd(OAc) 2 as catalyst. This sterically derived selectivity contrasts that for analogous arene acetoxylation.