40117-97-3

Basic information

• Product Name: 8-benzyl-8-aza-2-oxaspiro<4.5>decan-1-one
• CAS NO: 40117-97-3
• Molecular Weight: 245.321
• Mol File: 40117-97-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 8-benzyl-8-aza-2-oxaspiro<4.5>decan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 8-benzyl-8-aza-2-oxaspiro<4.5>decan-1-one(40117-97-3)
• EPA Substance Registry System: 8-benzyl-8-aza-2-oxaspiro<4.5>decan-1-one(40117-97-3)

Safety Data

• Hazardous Substances Data: 40117-97-3(Hazardous Substances Data)

Upstream product

• 40117-92-8 1-benzyl-4-carboxymethyl-piperidine-4-carboxylic acid 
• 100-44-7 benzyl chloride 
• 1126-09-6 4-carbethoxypiperidine 
• 75-21-8 oxirane 
• 24228-40-8 N-benzyl isonipecotic acid ethyl ester 
• 40117-96-2 1-benzyl-4-ethoxycarbonylmethyl-piperidine-4-carboxylic acid; hydrochloride 
• 40117-95-1 1-Benzyl-4-(carboxymethyl)-4-piperidinecarboxylic acid hydrochloride 
• 34702-66-4 8-benzyl-2-oxa-8-aza-spiro[4.5]decane-1,3-dione 

Relevant articles and documents

Synthesis and pharmacological evaluation of a new class of 2-oxo-8- azaspiro (4,5)decan-1-ones as analogues of the muscarinic agonist RS-86

A new series of 8-substituted-2-oxo-8-azapsiro (4,5)decan-1-ones has been synthesized and compounds tested for their cholinergic properties in comparison with the muscarinic agonist RS-86. Preliminary in vitro and in vivo pharmacological data indicate that none of them is provided with significant cholinergic effects either at central or peripheral level. A possible explanation for the lack of activity is given on the basis of conformational studies.