401504-39-0

Basic information

• Product Name: Benzeneacetic acid, a-[[(2-bromophenyl)methyl]amino]-, 1,1-dimethylethyl ester
• CAS NO: 401504-39-0
• Molecular Formula: C19H22BrNO2
• Molecular Weight: 376.293
• Mol File: 401504-39-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-[[(2-bromophenyl)methyl]amino]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-[[(2-bromophenyl)methyl]amino]-, 1,1-dimethylethyl ester(401504-39-0)
• EPA Substance Registry System: Benzeneacetic acid, a-[[(2-bromophenyl)methyl]amino]-, 1,1-dimethylethyl ester(401504-39-0)

Safety Data

• Hazardous Substances Data: 401504-39-0(Hazardous Substances Data)

Upstream product

• 53934-78-4 2-aminophenylacetic acid tert-butyl ester 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 

Downstream Products

• 401504-30-1 N-(benzyloxycarbonyl)-N-(2-bromobenzyl)phenylglycine tert-butyl ester 
• 401504-00-5 N-(2-bromobenzyl)-N-methylphenylglycine tert-butyl ester 

Relevant articles and documents

Palladium-catalyzed intramolecular α-arylation of α-amino acid esters

The Pd-catalyzed intramolecular α-arylation of α-amino acid esters is described. Starting from readily available amino acids, the synthesis of a variety of isoindolines and tetrahydroisoquinoline carboxylic acid esters has been accomplished. Additionally, fused tricyclic systems can be efficiently prepared from cyclic amino acid esters. Reaction conditions have been found that allow the use of tert-butyl ester and N-(benzyloxycarbonyl) protecting groups.