401565-92-2

Basic information

• Product Name: 1-BOC-4-(4-TRIFLUOROMETHYL-PHENYLAMINO)-PIPERIDINE
• Synonyms: 1-BOC-4-(4-TRIFLUOROMETHYL-PHENYLAMINO)-PIPERIDINE
• CAS NO: 401565-92-2
• Molecular Formula: C₁₇H₂₃F₃N₂O₂
• Molecular Weight: 344.37
• Mol File: 401565-92-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 408.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.216±0.06 g/cm3(Predicted)
• PKA: 2.88±0.20(Predicted)
• CAS DataBase Reference: 1-BOC-4-(4-TRIFLUOROMETHYL-PHENYLAMINO)-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-4-(4-TRIFLUOROMETHYL-PHENYLAMINO)-PIPERIDINE(401565-92-2)
• EPA Substance Registry System: 1-BOC-4-(4-TRIFLUOROMETHYL-PHENYLAMINO)-PIPERIDINE(401565-92-2)

Safety Data

• Hazardous Substances Data: 401565-92-2(Hazardous Substances Data)

Usage

Chemical structure

Piperidine derivative with a BOC protecting group and a substituted amino group with a trifluoromethylphenyl moiety

Functional groups

BOC protecting group, trifluoromethylphenyl moiety, and amino group

Application

Building block in organic synthesis for the preparation of pharmaceutical and agrochemical compounds

Potential use

Precursor for the synthesis of bioactive molecules in medicinal chemistry

Importance

Valuable intermediate in the production of complex organic compounds

Upstream product

• 455-14-1 4-trifluoromethylphenylamine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 87120-72-7 1-(tert-butoxycarbonyl)-4-aminopiperidine 

Downstream Products

• 501674-08-4 1-(tert-Butoxycarbonyl)-4-[N-[4-(trifluoromethyl)phenyl]-N-[3-(3,4,5-trimethoxyphenyl)benzyl]amino]piperidine 
• 1219625-90-7 tert-butyl 4-(2-bromo-N-(4-(trifluoromethyl)phenyl)acetamido)piperidine-1-carboxylate 
• 1350809-13-0 C₁₉H₂₁F₃N₂ 
• 1350809-24-3 C₂₀H₂₀F₃N₃ 
• 1350808-97-7 C₂₄H₂₉F₃N₂O₂ 
• 1350809-09-4 C₂₅H₂₈F₃N₃O₂ 

Relevant articles and documents

TEAD INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

NEW HETEROCYCLIC COMPOUNDS AS MONOACYLGLYCEROL LIPASE INHIBITORS

The invention provides new heterocyclic compounds having the general formula (I) wherein A, L, X, m, n, R1 and R2 are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.

NOVEL COMPOUNDS AS CALCIUM CHANNEL BLOCKERS

The present application relates to calcium channel inhibitors containing compounds of formula (I) wherein Ar1, Ar2, L1, L2, n, R1, R4, X and Y are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.