401575-24-4

Basic information

• Product Name: 2,2,2-Trifluoro-N-(2-pyridylMethyl)acetaMide, 96%
• Synonyms: 2,2,2-Trifluoro-N-(2-pyridylMethyl)acetaMide, 96%;N-(2-Pyridylmethyl)trifluoroacetamide;2,2,2-trifluoro-N-(pyridin-2-ylmethyl)acetamide
• CAS NO: 401575-24-4
• Molecular Formula: C₈H₇F₃N₂O
• Molecular Weight: 204.1491896
• Mol File: 401575-24-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 73-77℃
• Appearance: /
• CAS DataBase Reference: 2,2,2-Trifluoro-N-(2-pyridylMethyl)acetaMide, 96%(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-Trifluoro-N-(2-pyridylMethyl)acetaMide, 96%(401575-24-4)
• EPA Substance Registry System: 2,2,2-Trifluoro-N-(2-pyridylMethyl)acetaMide, 96%(401575-24-4)

Safety Data

• Hazardous Substances Data: 401575-24-4(Hazardous Substances Data)

Usage

General Description

2,2,2-Trifluoro-N-(2-pyridylMethyl)acetaMide, 96% is a chemical compound that is commonly used in organic synthesis and pharmaceutical research. It is a white crystalline solid with a purity of 96%, making it suitable for various laboratory applications. 2,2,2-Trifluoro-N-(2-pyridylMethyl)acetaMide, 96% has a trifluoromethyl group and a pyridylmethyl group, which give it unique properties and reactivity. It is commonly used as a building block in the synthesis of complex organic molecules and pharmaceutical intermediates. Its high purity and reactivity make it a valuable compound for chemical research and manufacturing processes.

Upstream product

• 3731-51-9 2-(Aminomethyl)pyridine 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 1128191-95-6 C₆H₈N₂*C₇H₈O₃S 
• 120221-68-3 3-(trifluoromethyl)imidazo[1,5-a]pyridine-1-carboxylic acid 

Relevant articles and documents

Distorted Copper(II) Complex with Unusually Short CF···Cu Distances

We find a Cu(II)-(L-CF3)2 complex (L-CF3 = 2,2,2-trifluoro-N-[2-(pyridin-2-yl)propan-2-yl]acetamide) with a distorted seesaw geometry. It has the shortest crystallographic CF···Cu distances yet reported, to the best of our knowledge (?), for which computational and experimental data indicate a secondary bonding interaction. A comparison with a CCl3 version and one without ligand backbone gem-dimethyl groups suggests a steric origin for the distorted geometry, resulting from the specific ligand interactions.

Efficient Preparation of Imidazo[1,5- a ]pyridine-1-carboxylic Acids

We report a novel and efficient approach to the synthesis of imidazo[1,5-a]pyridine-1-carboxylic acids. By using the reaction of 2-(aminomethyl)pyridine with acyl chlorides followed by one-pot treatment with trifluoroacetic anhydride, 2,2,2-trifluoro-1-im