40167-10-0

Basic information

• Product Name: 4-(PhenylMethoxy)-benzeneacetaldehyde
• Synonyms: 4-(PhenylMethoxy)-benzeneacetaldehyde;2-(4-Benzyloxyphenyl)acetaldehyde;4-Benzyloxyphenylacetaldehyde;4-PhenylMethoxyphenylacetaldehyde;BENZENEACETALDEHYDE, 4-(PHENYLMETHOXY)-
• CAS NO: 40167-10-0
• Molecular Formula: C₁₅H₁₄O₂
• Molecular Weight: 226
• Product Categories: Aromatics
• Mol File: 40167-10-0.mol
• Article Data: 22

Chemical Properties

• Boiling Point: 373.1±22.0 °C(Predicted)
• Appearance: /
• Density: 1.107±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• Solubility: CDCl3, CD3OD
• CAS DataBase Reference: 4-(PhenylMethoxy)-benzeneacetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(PhenylMethoxy)-benzeneacetaldehyde(40167-10-0)
• EPA Substance Registry System: 4-(PhenylMethoxy)-benzeneacetaldehyde(40167-10-0)

Safety Data

• Hazardous Substances Data: 40167-10-0(Hazardous Substances Data)

Usage

Description

4-(PhenylMethoxy)-benzeneacetaldehyde, also known as 4-(Phenylmethoxy)-benzeneacetaldehyde (CAS# 40167-10-0), is an organic compound characterized by its white solid appearance. It is primarily recognized for its utility in various organic synthesis processes, making it a valuable component in the chemical industry.

Uses

Used in Organic Synthesis:
4-(PhenylMethoxy)-benzeneacetaldehyde is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows it to serve as a building block for the creation of a wide range of molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-(PhenylMethoxy)-benzeneacetaldehyde is utilized as a starting material for the development of new drugs. Its versatility in organic synthesis enables the production of diverse drug candidates with potential therapeutic applications.
Used in Flavor and Fragrance Industry:
4-(PhenylMethoxy)-benzeneacetaldehyde is also employed in the flavor and fragrance industry, where it contributes to the creation of unique scents and flavors for various consumer products. Its chemical properties make it suitable for use in the formulation of perfumes, cosmetics, and the food industry.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 4-(PhenylMethoxy)-benzeneacetaldehyde is used as a precursor for the synthesis of various dyes and pigments. Its chemical structure allows for the development of a range of colorants used in textiles, plastics, and other applications requiring vibrant and stable colors.
Overall, 4-(PhenylMethoxy)-benzeneacetaldehyde is a versatile compound with a wide range of applications across different industries, including organic synthesis, pharmaceuticals, flavor and fragrance, and dyes and pigments. Its unique properties and utility in various synthesis processes make it an essential component in the development of new products and technologies.

Upstream product

• 61439-59-6 2-(4-benzyloxyphenyl)ethanol 
• 501-94-0 p-hydroxyphenethyl alcohol 
• 100-44-7 benzyl chloride 
• 36438-64-9 p-benzyloxystyrene 
• 100-39-0 benzyl bromide 
• 123-08-0 4-hydroxy-benzaldehyde 
• 82099-81-8 1-(benzyloxy)-4-(2-methoxyethenyl)benzene 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 68641-16-7 (4-benzyloxy-phenyl)-acetic acid methyl ester 

Downstream Products

• 75676-92-5 5-(p-benzyloxyphenyl)-trans-3-penten-2-one 
• 121537-69-7 4,4-ethylenedioxy-1-(4'-phenylmethoxyphenyl)cyclohexene 
• 178860-95-2 benzyl (2-(4-(benzyloxy)phenyl)-1-(diphenoxyphosphoryl)ethyl)carbamate 
• 205587-50-4 (E)-4-(4-benzyloxyphenyl)-2-butenoic acid ethyl ester 
• 410079-50-4 (R)-3-(4-benzyloxyphenyl)-2-hydroxypropionitrile 
• 946425-25-8 3-(4-(benzyloxy)phenyl)-2-hydroxypropanenitrile 
• 946425-26-9 C₂₄H₂₄O₄ 
• 951226-26-9 C₂₄H₂₃BrO₃ 
• 951227-04-6 C₂₅H₂₄N₂O₂S 
• 946425-28-1 C₁₈H₁₈N₂O₂S 
• 946425-48-5 C₂₂H₁₉ClO₃ 
• 951226-27-0 C₂₂H₁₈BrClO₂ 
• 951227-49-9 C₂₃H₁₉ClN₂OS 
• 946425-51-0 C₁₆H₁₃ClN₂OS 

Relevant articles and documents

NOVEL LYSOPHOSPHATIDIC ACID DERIVATIVE

PROBLEM TO BE SOLVED: To provide a compound that specifically activates an LPA4 receptor, and a pharmaceutical composition containing the same. SOLUTION: This invention relates to a novel lysophosphatidic acid derivative that has an agonistic action on an LPA4 receptor and is useful for the prevention and/or treatment of a disease with angiodysplasia caused by the LPA4 receptor, or a disease associated with angiopathy, or symptoms associated therewith. This invention also relates to a pharmaceutical composition containing the lysophosphatidic acid derivative. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

Synthesis and structure activity relationships of cyanopyridone based anti-tuberculosis agents

Mycobacterium tuberculosis, the causative agent of tuberculosis, relies on thymidylate kinase (MtbTMPK) for the synthesis of thymidine triphosphates and thus also DNA synthesis. Therefore, this enzyme constitutes a potential Achilles heel of the pathogen. Based on a previously reported MtbTMPK 6-aryl-substituted pyridone inhibitor and guided by two co-crystal structures of MtbTMPK with pyridone- and thymine-based inhibitors, we report the synthesis of a series of aryl-shifted cyanopyridone analogues. These compounds generally lacked significant MtbTMPK inhibitory potency, but some analogues did exhibit promising antitubercular activity. Analogue 11i demonstrated a 10-fold increased antitubercular activity (MIC H37Rv, 1.2 μM) compared to literature compound 5. Many analogues with whole-cell antimycobacterial activity were devoid of significant cytotoxicity.

Stereoselective Synthesis of Vinylboronates by Rh-Catalyzed Borylation of Stereoisomeric Mixtures

The stereoselective preparation of vinylboronates via rhodium-catalyzed borylation of E/Z mixtures of vinyl actetates is described, and this method was also extended to synthesis of vinyldiboronates. These transformations feature high functional group compatibility and mild reaction conditions. Control experiments support a mechanism that involved a Rh-catalyzed borylation-isomerization sequence. The isomerization of (Z)-vinylboronates to (E)-isomers was also demonstrated.