4022-43-9

Basic information

• Product Name: 1-Naphthaleneacetic acid, 4-phenyl-
• CAS NO: 4022-43-9
• Molecular Formula: C18H14O2
• Molecular Weight: 262.308
• Mol File: 4022-43-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Naphthaleneacetic acid, 4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Naphthaleneacetic acid, 4-phenyl-(4022-43-9)
• EPA Substance Registry System: 1-Naphthaleneacetic acid, 4-phenyl-(4022-43-9)

Safety Data

• Hazardous Substances Data: 4022-43-9(Hazardous Substances Data)

Usage

Type of compound

Organic

Derivative

Naphthaleneacetic acid

Plant hormone

Regulates growth and development of plants

Effects on plant growth

Potentially promotes root formation, increases flower and fruit production

Agricultural use

Growth regulator for various crops

Safety precautions

Handle carefully and follow guidelines to avoid negative effects on human health and the environment

Upstream product

• 5438-74-4 2-(4-bromonaphthalen-1-yl)acetic acid 
• 98-80-6 phenylboronic acid 

Downstream Products

• 1228298-51-8 ethyl 2-(4-phenylnaphthalen-1-yl)acetate 

Relevant articles and documents

Rational design of a pirinixic acid derivative that acts as subtype-selective PPARγ modulator

Peroxisome proliferator-activated receptor γ (PPARγ) is involved in glucose and lipid homeostasis. PPARγ agonists are in clinical use for the treatment of type 2 diabetes. Lately, a new class of selective PPARγ modulators (SPPARγMs) was developed, which are believed to show less side effects than full PPARγ agonists. We have previously shown that α-substitution of pirinixic acid, a moderate agonist of PPARα and PPARγ, leads to low micromolar active balanced dual agonists of PPARα and PPARγ. Herein we present modifications of pirinixic acid leading to subtype-selective PPARγ agonists and furthermore the development of a selective PPARγ modulator guided by molecular docking studies.

4- and 5-Aryl-l-naphthaleneacetic acids as antiinflammatory agents.

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