40230-92-0 Usage
Description
((3-METHOXYPHENYL)ETHYNYL)-TRIMETHYLSIL&, also known as (3-methoxyphenyl)ethynyl)-trimethylsilane, is a chemical compound that is a derivative of trimethylsilyl acetylene with a 3-methoxyphenyl group attached to the acetylene carbon. It has a unique structure and reactivity, making it a valuable tool for the synthesis of complex organic molecules.
Uses
Used in Organic Synthesis:
((3-METHOXYPHENYL)ETHYNYL)-TRIMETHYLSIL& is used as a building block in organic synthesis for the preparation of various functionalized organic molecules. Its unique structure and reactivity make it a valuable tool for creating complex organic molecules.
Used in Sonogashira Coupling Reaction:
((3-METHOXYPHENYL)ETHYNYL)-TRIMETHYLSIL& is commonly used as a reagent in the Sonogashira coupling reaction, a widely used method for the synthesis of carbon-carbon bonds. This reaction is an important tool in organic chemistry for forming new carbon-carbon bonds, which are essential for the creation of many organic compounds.
Used in Pharmaceutical Industry:
((3-METHOXYPHENYL)ETHYNYL)-TRIMETHYLSIL& has applications in the preparation of pharmaceuticals. Its unique structure and reactivity make it a valuable tool for the synthesis of complex organic molecules that can be used as active pharmaceutical ingredients or as intermediates in the synthesis of drugs.
Used in Agrochemical Industry:
((3-METHOXYPHENYL)ETHYNYL)-TRIMETHYLSIL& is also used in the preparation of agrochemicals. Its unique structure and reactivity make it a valuable tool for the synthesis of complex organic molecules that can be used as active ingredients in pesticides, herbicides, and other agricultural chemicals.
Used in Materials Science:
((3-METHOXYPHENYL)ETHYNYL)-TRIMETHYLSIL& has applications in materials science. Its unique structure and reactivity make it a valuable tool for the synthesis of complex organic molecules that can be used in the development of new materials with specific properties, such as polymers, coatings, and adhesives.
Check Digit Verification of cas no
The CAS Registry Mumber 40230-92-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,2,3 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 40230-92:
(7*4)+(6*0)+(5*2)+(4*3)+(3*0)+(2*9)+(1*2)=70
70 % 10 = 0
So 40230-92-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H16OSi/c1-13-12-7-5-6-11(10-12)8-9-14(2,3)4/h5-7,10H,1-4H3
40230-92-0Relevant articles and documents
Ortho-Carboranylphenoxyacetanilides as inhibitors of hypoxia-inducible factor (HIF)-1 transcriptional activity and heat shock protein (HSP) 60 chaperon activity
Li, Guangzhe,Azuma, Soyoko,Sato, Shinichi,Minegishi, Hidemitsu,Nakamura, Hiroyuki
, p. 2624 - 2628 (2015)
ortho-Carboranylphenoxy derivatives were synthesized and evaluated for their ability to inhibit hypoxia-induced HIF-1 transcriptional activity using a cell-based reporter gene assay. Among the compounds synthesized, compound 1d showed the most significant
Enantioselective synthesis of β-fluoro-β-aryl-α-aminopentenamides by organocatalytic [2,3]-sigmatropic rearrangement
Kasten, Kevin,Slawin, Alexandra M. Z.,Smith, Andrew D.
supporting information, p. 5182 - 5185 (2017/11/06)
The tetramisole-promoted catalytic enantioselective [2,3]-sigmatropic rearrangement of quaternary ammonium salts bearing a (Z)-3-fluoro-3-arylprop-2-ene group generates, after addition of benzylamine, a range of β-fluoro-β-aryl-α-aminopentenamides containing a stereogenic tertiary fluorine substituent. Cyclic and acyclic nitrogen substituents as well as various aromatic substituents are tolerated, giving the β-fluoro-β-aryl-α-aminopentenamide products in up to 76% yield, 96:4 dr, and 98:2 er.
Microwave-assisted copper- and palladium-catalyzed sonogashira-type coupling of aryl bromides and iodides with trimethylsilylacetylene
Lei, Yonghua,Hu, Tianhan,Wu, Xingsen,Wu, Yue,Xiang, Hua,Sun, Haopeng,You, Qidong,Zhang, Xiaojin
, p. 1100 - 1103 (2016/03/09)
An efficient and rapid method was developed for the synthesis of 1-aryl-2-(trimethylsilyl)acetylene. Copper and palladium-catalyzed sonogashira-type coupling of trimethylsilylacetylene and aryl bromides or iodides in the presence of triethylamine as base