40240-24-2

Basic information

• Product Name: Pyridine, 1,2,3,6-tetrahydro-5-methyl-1-(phenylmethyl)-
• Synonyms: Pyridine,1,2,3,6-tetrahydro-5-methyl-1-(phenylmethyl);1-benzyl-3-methyl-1,2,5,6-tetrahydropyridine;1-benzyl-5-methyl-1,2,3,6-tetrahydro-pyridine
• CAS NO: 40240-24-2
• Molecular Formula: C13H17N
• Molecular Weight: 187.285
• Mol File: 40240-24-2.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 270.2±9.0 °C(Predicted)
• Density: 1.000±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Pyridine, 1,2,3,6-tetrahydro-5-methyl-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 1,2,3,6-tetrahydro-5-methyl-1-(phenylmethyl)-(40240-24-2)
• EPA Substance Registry System: Pyridine, 1,2,3,6-tetrahydro-5-methyl-1-(phenylmethyl)-(40240-24-2)

Safety Data

• Hazardous Substances Data: 40240-24-2(Hazardous Substances Data)

Upstream product

• 58416-59-4 1-benzyl-3-methylpyridin-1-ium bromide 
• 6560-72-1 1-benzyl-3-methyl-piperidin-3-ol 
• 75-05-8 acetonitrile 
• 143104-60-3 Benzyl-((E)-hex-3-enyl)-(2-methyl-allyl)-amine 
• 108-99-6 3-Methylpyridine 
• 100-39-0 benzyl bromide 
• 16214-99-6 N-benzyl-3-methyl-pyridinium chloride 

Downstream Products

• 212008-89-4 1-Benzyl-3-methyl-1,2,5,6-tetrahydro-pyridine-2-carbonitrile 
• 162465-70-5 1-benzyl-4-methoxy-3-methyl-1,4,5,6-tetrahydropyridine 
• 212008-99-6 1-benzyl-3-methyl-1,2,5,6-tetrahydropyridine N-oxide 

Relevant articles and documents

Reactions of Aminopentadienal Derivatives with 5,6-Dihydropyridinium Salts as an Approach to Manzamine Alkaloids Based upon Biogenetic Considerations

Recent results from our laboratory have prompted us to introduce a modification of the original Baldwin proposal for the biosynthesis of manzamine alkaloids. In this new model, aminopentadienal derivatives of general structures 2 or 3 can not only cyclize to give pyridinium salts such as cyclostellettamines but also react with 5,6-dihydropyridinium salts 1 leading to species such as 6 or 7, which would be key intermediates in the syntheses of manzamine A and halicyclamine B. On the basis of the chemistry depicted in Scheme 2, model reactions of dienes 9, 10, 12, and 13 with salts 1 have been investigated. Diene 9 gave an interesting rearrangement product 15a, while dienes 10 and 12 gave halicyclamine- and manzamine-type adducts 19 and 23, respectively. In addition, glutaconaldehyde derivative 13 gave adduct 32 possessing some characteristic features of sarain A.

Azaquinazoline Inhibitors Of Atypical Protein Kinase C

The present application provides a compound of formula (I) and/or a salt thereof, wherein R1, G, and X are as defined herein. A compound of formula (I) and/or its salts have aPKC inhibitory activity, and may be used to treat proliferative disor

IMIDAZOLE DERIVATIVES AND METHODS OF USE THEREOF FOR IMPROVING THE PHARMACOKINETICS OF A DRUG

The present invention relates to Imidazole Derivatives of Formula (I), and pharmaceutically acceptable salts thereof, wherein A, B, Y, R1 and R2 are as defined herein. The present invention also relates to compositions comprising at least one Imidazole Derivative, and and methods of using the Imidazole Derivatives for inhibiting CYP450 3A. Inhibition of CYP450 3A can be used to improve the pharmacokinetics of a drug that is metabolized by CYP450 3A4.