40255-47-8

Basic information

• Product Name: 3-(4-(4-methylphenyl)-1-piperazinyl)propylamine
• Synonyms: 3-(4-(4-methylphenyl)-1-piperazinyl)propylamine
• CAS NO: 40255-47-8
• Molecular Weight: 233.357
• Mol File: 40255-47-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-(4-(4-methylphenyl)-1-piperazinyl)propylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-(4-methylphenyl)-1-piperazinyl)propylamine(40255-47-8)
• EPA Substance Registry System: 3-(4-(4-methylphenyl)-1-piperazinyl)propylamine(40255-47-8)

Safety Data

• Hazardous Substances Data: 40255-47-8(Hazardous Substances Data)

Usage

Use

antidepressant and antipsychotic medication

Pharmacological action

selective antagonist for serotonin 5-HT1A and 5-HT1B receptors

Function

regulates mood and anxiety

Therapeutic potential

treatment of depressive disorders and other psychiatric conditions

Research interest

modulation of neurochemical responses in the brain, neuroscience research

Upstream product

• 75426-49-2 3-[4-(4-methylphenyl)piperazin-1-yl]propanenitrile 
• 763877-21-0 N-[3-(4-p-tolyl-piperazin-1-yl)-propyl]-phthalimide 
• 39593-08-3 (4-methylphenyl)piperazine 

Downstream Products

• 1240266-75-4 C₂₇H₃₆N₄O*ClH 
• 1044529-29-4 Z₀₆₆-0019 
• 90619-44-6 1,8,8-Trimethyl-3-[3-(4-p-tolyl-piperazin-1-yl)-propyl]-3-aza-bicyclo[3.2.1]octane-2,4-dione; hydrochloride 
• 90619-37-7 2-[3-(4-p-Tolyl-piperazin-1-yl)-propyl]-3a,4,7,7a-tetrahydro-isoindole-1,3-dione; hydrochloride 
• 129010-98-6 2-Methoxy-5-sulfamoyl-N-[3-(4-p-tolyl-piperazin-1-yl)-propyl]-benzamide 

Relevant articles and documents

Synthesis and biological evaluation of oxazole derivatives as T-type calcium channel blockers

T-type calcium channel is one of therapeutic targets for the treatment of cardiovascular diseases and neuropathic pain. In this study, as a part of our ongoing efforts to develop potent T-type calcium channel blockers, we designed oxazole derivatives subs

POTENTIAL NEUROLEPTICS OF THE ORTHOPRAMIDE SERIES; SYNTHESIS OF N-(3-(TERT.AMINO)PROPYL)-5-SULFAMOYL-2-METHOXYBENZAMIDES

Heating ethyl 5-sulfamoyl-2-methoxybenzoate with a series of twelve 3-(tert.amino)propylamines (IIIa-IIIl) afforded the title compounds IIa-IIl which were transformed to salts and subjected to pharmacological screening as potential neuroleptics of the sulpiride series.Only compounds IId (hydrogen oxalate, VUFB-15 453) and IIg (methanesulfonate, VUFB-15 397) showed indications of the desired psychotropic activity.

Synthesis and pharmacology of 1-(4-aryl-1-piperazinyl-alkyl)-4-(4-methoxyphenyl) piperidine-2,6-diones: Tranquilizers

-