402734-81-0

Basic information

• Product Name: 5'-O-(4-monomethoxytrithylthio)-3'-O-tert-butyldimethylsilylthymidine
• Synonyms: 5'-O-(4-monomethoxytrithylthio)-3'-O-tert-butyldimethylsilylthymidine
• CAS NO: 402734-81-0
• Molecular Weight: 660.907
• Mol File: 402734-81-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5'-O-(4-monomethoxytrithylthio)-3'-O-tert-butyldimethylsilylthymidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5'-O-(4-monomethoxytrithylthio)-3'-O-tert-butyldimethylsilylthymidine(402734-81-0)
• EPA Substance Registry System: 5'-O-(4-monomethoxytrithylthio)-3'-O-tert-butyldimethylsilylthymidine(402734-81-0)

Safety Data

• Hazardous Substances Data: 402734-81-0(Hazardous Substances Data)

Upstream product

• 383401-03-4 4-monomethoxytriphenylmethanethiol 
• 847-83-6 p-methoxytrityl alcohol 
• 40733-27-5 3'-O-(t-butyldimethylsilyl)thymidine 
• 402734-78-5 4-monomethoxytritylsulfenyl chloride 

Downstream Products

• 402734-83-2 3-N-(4-monomethoxytrithylthio)thymidine 

Relevant articles and documents

Synthesis of pentathymidylate using a 4-monomethoxytritylthio (MMTrS) group as a 5′-hydroxyl protecting group: Toward oligonucleotide synthesis without acid treatment

A phosphoramidite unit having 4-monomethoxytritylthio as a new 5′-hydroxyl protecting group was prepared and employed in oligonucleotide synthesis. The new phosphoramidite enabled the synthesis of oligonucleotides without the use of acids such as TFA or DCA.