402824-96-8

Basic information

• Product Name: N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxode
• Synonyms: HCTZ-CH2-HCTZ;Hydrochlorothiazide Impurity C;N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxode;N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamid;N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonamide Hydrochlorothiazide Impurity C;N-[[7-(AMinosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]Methyl]-6-chloro-3,4-dihydro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonaMide;Hydrochlorothiazide IMpurity-C(EP);N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-1,1-dioxo-2H-1,2,4-benzothiadiazine-7-sulfonamide\nHydrochlorothiazide Impurity C:
• CAS NO: 402824-96-8
• Molecular Formula: C15H16Cl2N6O8S4
• Molecular Weight: 607.49
• Product Categories: Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals
• Mol File: 402824-96-8.mol
• Article Data: 0

Chemical Properties

• Melting Point: 208-212?C
• Boiling Point: 930.9°C at 760 mmHg
• Flash Point: 516.8°C
• Appearance: /
• Density: 1.764g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.667
• Storage Temp.: -20°C Freezer
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 5.72±0.40(Predicted)
• CAS DataBase Reference: N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxode(CAS DataBase Reference)
• NIST Chemistry Reference: N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxode(402824-96-8)
• EPA Substance Registry System: N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxode(402824-96-8)

Safety Data

• Hazardous Substances Data: 402824-96-8(Hazardous Substances Data)

Usage

Description

N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxode is a complex organic compound with a chemical structure that features a benzothiadiazine core, with various functional groups such as aminosulfonyl, chloro, and sulfonamide attached. It is a white to off-white solid and is known to be an impurity in bulk Hydrochlorothiazide.

Uses

Used in Pharmaceutical Industry:
N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxode is used as an impurity in the production of Hydrochlorothiazide for the pharmaceutical industry. Its presence is important for quality control and ensuring the safety and efficacy of the final drug product.
Used in Quality Control and Analysis:
N-[[7-(Aminosulfonyl)-6-chloro-2,3-dihydro-1,1-dioxo-4H-1,2,4-benzothiadiazin-4-yl]methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxode is also used in the quality control and analysis of Hydrochlorothiazide, a medication commonly used to treat high blood pressure and other conditions. By monitoring the levels of this impurity, manufacturers can ensure that the drug meets the required standards for purity and effectiveness.
Used in Research and Development:
In the field of research and development, this compound may be used to study the effects of impurities on the properties and performance of pharmaceuticals. Understanding the role of such impurities can help in the development of better drug formulations and improved manufacturing processes.

InChI:InChI=1/C15H16Cl2N6O8S4/c16-8-1-10-14(34(28,29)20-5-19-10)4-13(8)33(26,27)21-6-23-7-22-35(30,31)15-3-12(32(18,24)25)9(17)2-11(15)23/h1-4,19-22H,5-7H2,(H2,18,24,25)