40290-36-6 Usage
Description
1,2-Dipalmitoyl-3-iododeoxy-rac-glycerol, also known as 1,2-DIPALMITOYL-3-IODO-RAC-3-DEOXYGLYCEROL, is a synthetic compound derived from glycerol. It is characterized by the presence of two palmitoyl groups and an iodine atom, which contribute to its unique properties. 1,2-DIPALMITOYL-3-IODO-RAC-3-DEOXYGLYCEROL has been found to have potential applications in various fields due to its amphipathic nature and ability to form micellar structures.
Uses
1,2-DIPALMITOYL-3-IODO-RAC-3-DEOXYGLYCEROL is used as a component in the preparation of glycolipid amphipathic micellar delivery systems for DNA and RNA biological active polyions. The expression is: 1,2-DIPALMITOYL-3-IODO-RAC-3-DEOXYGLYCEROL is used as a component for the formation of micellar delivery systems for [application reason].
Used in Pharmaceutical Industry:
1,2-DIPALMITOYL-3-IODO-RAC-3-DEOXYGLYCEROL is used as a component in the development of drug delivery systems, specifically for the encapsulation and delivery of DNA and RNA molecules. This application is particularly relevant in the field of gene therapy, where the efficient delivery of genetic material is crucial for the treatment of various diseases and conditions.
The use of 1,2-DIPALMITOYL-3-IODO-RAC-3-DEOXYGLYCEROL in the creation of micellar delivery systems allows for the protection of sensitive DNA and RNA molecules from degradation, while also facilitating their transport across biological barriers. This enhances the bioavailability and therapeutic efficacy of these genetic materials, making them more effective in their intended applications.
Check Digit Verification of cas no
The CAS Registry Mumber 40290-36-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,2,9 and 0 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 40290-36:
(7*4)+(6*0)+(5*2)+(4*9)+(3*0)+(2*3)+(1*6)=86
86 % 10 = 6
So 40290-36-6 is a valid CAS Registry Number.
40290-36-6Relevant articles and documents
A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES
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Page/Page column 56, (2021/02/12)
The present invention relates to a method for modifying and purifying peptides comprising an immobilizing step, a modification step and a releasing step. In the immobilizing step, a crude linker-tagged peptide L-P is coupled to a solid support yielding an immobilized linker-tagged peptide S-L-P. Subsequently, the immobilized linker-tagged peptide S-L-P is modified with one or more organic molecules yielding an immobilized linker-tagged peptide S-L-mP. Finally, the modified peptide is released via a reduced intermediate RI. The linker molecule is a compound of formula 1, X-Tbb-Vaa-U-Y-Z (1), which can be coupled to a purification resin via the moiety X and to a peptide via the moiety Y under the release of the leaving group Z. T is an optional spacer moiety and V is an optional electron withdrawing moiety. U is an aryl or 5- or 6-membered heteroaryl moiety bound to at least one electron withdrawing moiety V, W or E. The linker is stable under acidic conditions and releases the peptide upon addition of a reducing agent.
SYNTHESIS OF THIO ANALOG OF A GLYCOSYLDIGLYCERIDE
Bityukova, I. I.,Volkova, L. V.,Evstigneeva, R. P.
, p. 829 - 831 (2007/10/02)
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Synthesis of dipalmitoyl-L-alpha-glycerophosphoric acid derivatives, as possible intermediates for synthesis of glycerylphosphatides.
STANACEV,KATES
, p. 297 - 300 (2007/10/12)
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