40292-15-7

Basic information

• Product Name: 4-BROMO-4'-NITROBENZOPHENONE
• Synonyms: 4-BROMO-4'-NITROBENZOPHENONE;(4-bromophenyl)(4-nitrophenyl)methanone
• CAS NO: 40292-15-7
• Molecular Formula: C₁₃H₈BrNO₃
• Molecular Weight: 306.11
• Mol File: 40292-15-7.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 438.4°C at 760 mmHg
• Flash Point: 218.9°C
• Appearance: /
• Density: 1.565g/cm³
• Vapor Pressure: 6.93E-08mmHg at 25°C
• Refractive Index: 1.637
• CAS DataBase Reference: 4-BROMO-4'-NITROBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-4'-NITROBENZOPHENONE(40292-15-7)
• EPA Substance Registry System: 4-BROMO-4'-NITROBENZOPHENONE(40292-15-7)

Safety Data

• Hazardous Substances Data: 40292-15-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H8BrNO3/c14-11-5-1-9(2-6-11)13(16)10-3-7-12(8-4-10)15(17)18/h1-8H

Upstream product

• 108-86-1 bromobenzene 
• 100-14-1 4-nitrobenzyl chloride 
• 122-04-3 4-nitro-benzoyl chloride 
• 555-16-8 4-nitrobenzaldehdye 
• 148651-39-2 (4-bromophenyl)zinc iodide 
• 62-23-7 4-nitro-benzoic acid 
• 5467-74-3 4-Bromophenylboronic acid 
• 636-98-6 p-nitrobenzene iodide 
• 201230-82-2 carbon monoxide 
• 14062-25-0 Ethyl 4-bromophenylacetate 
• 98-95-3 nitrobenzene 
• 10372-94-8 (4-bromophenyl)(4-nitrophenyl)methan-1-ol 
• 106-37-6 1.4-dibromobenzene 

Downstream Products

• 40292-19-1 (4-aminophenyl)(4-bromophenyl)methanone 
• 87424-32-6 4-bromo-3,4'-dinitro benzophenone 
• 33092-28-3 2-[4-(4-Bromo-benzoyl)-phenyl]-2-phenyl-butyronitrile 
• 33092-27-2 2-[4-(4-Bromo-benzoyl)-phenyl]-2,3-diphenyl-propionitrile 
• 33092-19-2 {4-[4-(4-Bromo-benzoyl)-phenyl-NNO-azoxy]-phenyl}-(4-bromo-phenyl)-methanone 
• 55233-12-0 2-[4-(4-Bromo-benzoyl)-phenyl]-2-phenyl-propionitrile 
• 68271-77-2 4-(4-nitrobenzoyl)benzonitrile 
• 146470-28-2 C₁₄H₁₂BrN₅O₂*ClH 
• 861344-46-9 3,4'-diamino-4-bromo-benzophenone 
• 159106-14-6 4-nitro-4'-phenylethynylbenzophenone 
• 1321599-95-4 4-bromo-4'-nitrobenzophenone hydrazone 
• 10372-94-8 (4-bromophenyl)(4-nitrophenyl)methan-1-ol 

Relevant articles and documents

AIBN initiated functionalization of the benzylic sp3 C[sbnd]H and C[sbnd]C bonds in the presence of dioxygen

A sp3 C[sbnd]H bond functionalization and C[sbnd]C bond cleavage were realized by AIBN/O2 catalyst system, providing a series of benzophenones under mild reaction conditions. The mechanistic study shows that a peroxide intermediate is involved in this transformation, and in the case of diphenylmethanes, the sp3 C[sbnd]C bond is cleaved through the peroxide rearrangement, which might provides a new way to cleave relatively strong C[sbnd]C bond and be applied to more general C[sbnd]C bond activation.

Dirhodium-Catalyzed Enantioselective B?H Bond Insertion of gem-Diaryl Carbenes: Efficient Access to gem-Diarylmethine Boranes

The scarcity of reliable methods for synthesizing chiral gem-diarylmethine borons limits their applications. Herein, we report a method for highly enantioselective dirhodium-catalyzed B?H bond insertion reactions with diaryl diazomethanes as carbene precursors. These reactions afforded chiral gem-diarylmethine borane compounds in high yield (up to 99 % yield), high activity (turnover numbers up to 14 300), high enantioselectivity (up to 99 % ee) and showed unprecedented broad functional group tolerance. The borane compounds synthesized by this method could be efficiently transformed into diaryl methanol, diaryl methyl amine, and triaryl methane derivatives with good stereospecificity. Mechanistic studies suggested that the borane adduct coordinated to the rhodium catalyst and thus interfered with decomposition of the diazomethane, and that insertion of a rhodium carbene (generated from the diaryl diazomethane) into the B?H bond was most likely the rate-determining step.

Transition-Metal-Free Regiospecific Aroylation of Nitroarenes Using Ethyl Arylacetates at Room Temperature

A novel regiospecific C(sp3)-C(sp2) coupling between ethyl arylacetates and nitroarenes has been developed to deliver biaryl ketones in excellent yields. The protocol is metal-free, mild, and compatible with a number of functional groups on both of the reacting partners.