402958-25-2 Usage
Description
(1S,3AR,6AS)-OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID ETHYL ESTER, also known as a bicyclic pyrrole derivative, is a chemical compound with a unique molecular structure. It is characterized by its octahydrocyclopenta[c]pyrrole framework and an ester functional group attached to the carboxylic acid. (1S,3AR,6AS)-OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID ETHYL ESTER has potential applications in the pharmaceutical industry due to its specific chemical properties and interactions with biological targets.
Uses
Used in Pharmaceutical Industry:
(1S,3AR,6AS)-OCTAHYDRO-CYCLOPENTA[C]PYRROLE-1-CARBOXYLIC ACID ETHYL ESTER is used as a key intermediate compound for the synthesis of hepatitis C virus (HCV) protease inhibitors. These inhibitors play a crucial role in the development of antiviral drugs that target and block the activity of HCV protease, an enzyme essential for the replication of the virus. By inhibiting this enzyme, the compound can help in the treatment and management of hepatitis C infections.
Check Digit Verification of cas no
The CAS Registry Mumber 402958-25-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,2,9,5 and 8 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 402958-25:
(8*4)+(7*0)+(6*2)+(5*9)+(4*5)+(3*8)+(2*2)+(1*5)=142
142 % 10 = 2
So 402958-25-2 is a valid CAS Registry Number.
InChI:InChI=1S/C10H17NO2/c1-2-13-10(12)9-8-5-3-4-7(8)6-11-9/h7-9,11H,2-6H2,1H3/t7-,8-,9-/m0/s1
402958-25-2Relevant articles and documents
Telaprevir intermediate preparation method
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, (2017/07/14)
The invention relates to a preparation method of cyclopentane [c] pyrrole compound (formula I), and the method comprises following steps: taking 3-diaza-bicyclo [3.3.0] octane as the raw material, and then subjecting the raw material to cyanation, hydrolysis and esterification reactions so as to obtain the target product. The preparation method has the advantages of simple and easy operation, high yield, high product purity, and suitability for industrial production.
Discovery of a novel bicycloproline P2 bearing peptidyl α-ketoamide LY514962 as HCV protease inhibitor
Yip, Yvonne,Victor, Frantz,Lamar, Jason,Johnson, Robert,Wang, Q. May,Barket, Donna,Glass, John,Jin, Ling,Liu, Lifei,Venable, Daryl,Wakulchik, Mark,Xie, Congping,Heinz, Beverly,Villarreal, Elcira,Colacino, Joe,Yumibe, Nathan,Tebbe, Mark,Munroe, John,Chen, Shu-Hui
, p. 251 - 256 (2007/10/03)
We describe herein the design, syntheses and evaluation of a number of bicycloproline P2 bearing HCV protease inhibitors endowed with impressive enzyme potency, enzyme selectivity, cellular activity and favorable ADME profiles.
