40334-34-7Relevant articles and documents
Phosphonamidates are the first phosphorus-based zinc binding motif to show inhibition of β-class carbonic anhydrases from bacteria, fungi, and protozoa
Alissa, Siham A.,Alghulikah, Hanan A.,Alothman, Zeid A.,Osman, Sameh M.,Del Prete, Sonia,Capasso, Clemente,Nocentini, Alessio,Supuran, Claudiu T.
, p. 59 - 64 (2019/11/11)
A primary strategy to combat antimicrobial resistance is the identification of novel therapeutic targets and anti-infectives with alternative mechanisms of action. The inhibition of the metalloenzymes carbonic anhydrases (CAs, EC 4.2.1.1) from pathogens (
