40341-23-9

Basic information

• Product Name: 3-forMylthiophen-2-aMine
• Synonyms: 3-forMylthiophen-2-aMine;2-Amino-3-formylthiophene;2-Amino-3-thiophenecarboxaldehyde;2-aminothiophene-3-carbaldehyde
• CAS NO: 40341-23-9
• Molecular Formula: C₅H₅NOS
• Molecular Weight: 127.1643
• Mol File: 40341-23-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 294℃
• Flash Point: 131℃
• Appearance: /
• Density: 1.369
• CAS DataBase Reference: 3-forMylthiophen-2-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-forMylthiophen-2-aMine(40341-23-9)
• EPA Substance Registry System: 3-forMylthiophen-2-aMine(40341-23-9)

Safety Data

• Hazardous Substances Data: 40341-23-9(Hazardous Substances Data)

Upstream product

• 163079-30-9 2-Azido-3-formylthiophene 
• 41057-04-9 2-nitro-3-thiophenecarbaldehyde 
• 849805-82-9 2-(2-Nitro-thiophen-3-yl)-[1,3]dioxolane 

Relevant articles and documents

NOVEL ANTIMALARIA AGENT CONTAINING HETEROCYCLIC COMPOUND

Disclosed is an antimalarial agent containing a compound represented by the formula: [wherein A1 represents a 3-pyridyl group that may have a substituent, a 6-quinolyl group that may have a substituent, or the like; X1 represents a group represented by the formula -C(=O)-NH- or the like; E represents a furyl group, a thienyl group or a phenyl group; with the proviso that A1 may have one to three substituents, and E has one of two substituents] or a salt thereof or hydrates thereof.

Synthesis of thienoimidazo[4,5-b]pyridines and thenylidenoimidazolinones

The two isomers 2-amino-1-methylimidazo[4,5-b]thieno[3,2-e]pyridine (3) and 2-amino-1-methylimidazo[4,5-b]thieno[2,3-e]pyridine (4) were synthesized by the Friedlaender reaction starting from creatinine and the appropriate aminothiophenecarbaldehydes (11 and 13). Creatinine was also condensed with 2-nitro-3-thiophenecarbaldehyde (10) in ethylene glycol to yield the 2-amino-1-methyl-5-[2-(2-nitro-3-thenylidene)]-2-imidazolin-4-one (7a), with 3-amino-2-thiophenecarbaldehyde (13) under Perkin conditions to yield 2-acetamido-5-[2-(3-acetamido-2-thenylidene)]-1-methyl-2-imidazolin-4-on e (8), and with 4-azido-3-thiophenecarbaldehyde (17) in acetic acid to yield 2-amino-5-[2-(4-azido-3-thenylidene)]-1-methyl-2-imidazolin-4-one (9). The thenylidenoimidazolinone (8) was converted into compound (4).{A figure is presented}.

Hexamethyldisilathiane: Its Use in the Conversion of Aromatic and Heteroaromatic Azides to Amines

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