403793-24-8

Basic information

• Product Name: 1-Propanamine, 3-[(4-bromophenyl)thio]-N,N-dimethyl-
• CAS NO: 403793-24-8
• Molecular Formula: C11H16BrNS
• Molecular Weight: 274.225
• Mol File: 403793-24-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Propanamine, 3-[(4-bromophenyl)thio]-N,N-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanamine, 3-[(4-bromophenyl)thio]-N,N-dimethyl-(403793-24-8)
• EPA Substance Registry System: 1-Propanamine, 3-[(4-bromophenyl)thio]-N,N-dimethyl-(403793-24-8)

Safety Data

• Hazardous Substances Data: 403793-24-8(Hazardous Substances Data)

Upstream product

• 5407-04-5 3-(dimethylamino)propyl chloride hydrochloride 
• 106-53-6 para-bromobenzenethiol 

Downstream Products

• 403793-26-0 1-[3-(N,N-Dimethylamino)propylsulphonyl]-4-bromobenzene 

Relevant articles and documents

CDK9 Kinase inhibitors

The present application relates to CDK9 kinase inhibitors which provide a compound of formula (I) or a stereoisomer thereof. A solvate, a metabolite, a pharmaceutically acceptable salt or prodrug, and a pharmaceutical composition comprising the same. Also provided are the use of compounds and pharmaceutical compositions in the manufacture of a medicament for the treatment of cancer.

DERIVATIVES OF 4- (IMIDAZOL-5-YL)-2-(4-SULFOANILINO) PYRIMIDINE WITH CDK INHIBITORY ACTIVITY

Compounds of the formula (I): wherein R1, R2, R3, R4, R5 and p are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man.