404034-90-8

Basic information

• Product Name: Acetamide, 2-bromo-N-[6-[6-[[[(2-nitrophenyl)sulfonyl]amino]methyl]-2-pyridinyl]hexyl ]-
• CAS NO: 404034-90-8
• Molecular Formula: C20H25BrN4O5S
• Molecular Weight: 513.412
• Mol File: 404034-90-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-bromo-N-[6-[6-[[[(2-nitrophenyl)sulfonyl]amino]methyl]-2-pyridinyl]hexyl ]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-bromo-N-[6-[6-[[[(2-nitrophenyl)sulfonyl]amino]methyl]-2-pyridinyl]hexyl ]-(404034-90-8)
• EPA Substance Registry System: Acetamide, 2-bromo-N-[6-[6-[[[(2-nitrophenyl)sulfonyl]amino]methyl]-2-pyridinyl]hexyl ]-(404034-90-8)

Safety Data

• Hazardous Substances Data: 404034-90-8(Hazardous Substances Data)

Upstream product

• 404034-89-5 {2-[6-(5-cyanopentyl)pyridin-2-yl]methyl}-2-nitrobenzenesulfonamide 
• 404034-88-4 N-(6-bromopyridin-2-ylmethyl)-2-nitrobenzenesulfonamide 
• 188637-63-0 (6-bromopyridin-2-yl)methanamine 
• 1694-92-4 2-Nitrobenzenesulfonyl chloride 
• 598-21-0 2-Bromoacetyl bromide 

Downstream Products

• 404034-91-9 3-(2-nitrobenzenesulfonyl)-3,6,17-triazabicyclo[11,3,1]heptadeca-1⁽¹⁷⁾,13,15-trien-5-one 

Relevant articles and documents

Palladium(0)-catalyzed coupling of organozinc iodide reagents with bromopyridines: Synthesis of selectively protected pyridine-containing azamacrocycles

The synthesis of azamacrocycles in which the ring nitrogens are regioselectively functionalized is described. An organozinc palladium(0)-catalyzed coupling with an appropriately functionalized bromopyridine generated a key intermediate, which was transformed in two steps to a desired precursor and subjected to an intramolecular N-alkylation to effect a macrocyclization affording selectively protected azamacrocycles 1-3.