40432-40-4 Usage
General Description
1-Benzyl-azetidine-2-carboxylic acid amide, also known as benzylazetidin-2-one, is a chemical compound consisting of a benzene ring attached to an azetidine ring with a carboxylic acid and an amide functional group. It is commonly used as a building block in organic synthesis for the preparation of various pharmaceuticals and biologically active compounds. 1-BENZYL-AZETIDINE-2-CARBOXYLIC ACID AMIDE has shown potential as an antidepressant and analgesic, and it has also demonstrated antimicrobial and antifungal properties. Additionally, research has suggested its potential as a potent inhibitor of protein tyrosine phosphatase 1B, making it a promising lead compound for the development of new antidiabetic drugs. Overall, 1-benzyl-azetidine-2-carboxylic acid amide has a wide range of applications in medicinal chemistry and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 40432-40-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,4,3 and 2 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 40432-40:
(7*4)+(6*0)+(5*4)+(4*3)+(3*2)+(2*4)+(1*0)=74
74 % 10 = 4
So 40432-40-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N2O/c12-11(14)10-6-7-13(10)8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H2,12,14)
40432-40-4Relevant articles and documents
Enzymatic resolution of methyl N-alkyl-azetidine-2-carboxylates by Candida antarctica lipase-mediated ammoniolysis
Starmans, Wim A. J.,Doppen, Roy G.,Thijs, Lambertus,Zwanenburg, Binne
, p. 429 - 435 (2007/10/03)
A facile method for the synthesis of optically active azetidine-2- carboxylic acid derivatives is presented Racemic N-alkylated azetidine esters are resolved by lipase from Candida antarctica in an ammoniolysis reaction, and both the S-amide and the R-ester are obtained with excellent stereoselectivity.
