40463-09-0

Basic information

• Product Name: 4-methyl-1-phenylpentan-3-one
• Synonyms: 4-methyl-1-phenylpentan-3-one;1-Phenyl-4-methyl-3-pentanone;2-Methyl-5-phenyl-3-pentanone;4-Methyl-1-phenyl-3-pentanone
• CAS NO: 40463-09-0
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25484
• EINECS: 254-930-9
• Mol File: 40463-09-0.mol
• Article Data: 42

Chemical Properties

• Boiling Point: 254.8 °C at 760 mmHg
• Flash Point: 101 °C
• Appearance: /
• Density: 0.948 /cm³
• Vapor Pressure: 0.0169mmHg at 25°C
• Refractive Index: 1.496
• CAS DataBase Reference: 4-methyl-1-phenylpentan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-1-phenylpentan-3-one(40463-09-0)
• EPA Substance Registry System: 4-methyl-1-phenylpentan-3-one(40463-09-0)

Safety Data

• Hazardous Substances Data: 40463-09-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16O/c1-10(2)12(13)9-8-11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3

Upstream product

• 2021-28-5 ethyl dihydrocinnamate 
• 1068-55-9 isopropylmagnesium chloride 
• 3160-32-5 (1E)-4-methyl-1-phenylpent-1-en-3-one 
• 60550-54-1 2-methyl-5-phenylpent-1-en-3-one 
• 79-31-2 isobutyric Acid 
• 501-52-0 3-Phenylpropionic acid 
• 68426-07-3 (+/-)-1-phenyl-5-methylpentan-3-ol 
• 40463-08-9 2,2-dimethyl-3-(2-phenylethyl)oxirane 
• 3277-89-2 phenethylmagnesium bromide 
• 25179-23-1 lithium dimethylacetate 
• 78-82-0 Isobutyronitrile 
• 90878-19-6 phenethylmagnesium chloride 
• 3160-32-5 4-methyl-1-phenyl-1-penten-3-one 
• 144882-91-7 5-phenyl-2-(p-tolylsulfinyl)-3-pentanone 

Downstream Products

• 260257-61-2 (RS)-3-hydroxy-3-(2-phenethyl)-4-methylpentanoic acid tert-butyl ester 
• 249728-38-9 4-hydroxy-6-isopropyl-6-phenethyl-5,6-dihydro-pyran-2-one 
• 249728-23-2 ethyl-sulfamic acid 5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl ester 
• 260257-60-1 (RS)-3-hydroxy-3-(2-phenethyl)-4-methylpentanoic acid 
• 260257-65-6 (R)-3-hydroxy-3-(2-phenethyl)-4-methylpentanoic acid 
• 260257-62-3 (S)-3-hydroxy-3-(2-phenethyl)-4-methylpentanoic acid 
• 260257-94-1 3-(2-tert-butyl-4-hydroxy-5-methyl-phenylsulfanyl)-4-hydroxy-6-isopropyl-6-phenethyl-5,6-dihydro-pyran-2-one 
• 263842-69-9 N-[5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-methanesulfonamide 
• 263842-98-4 pyridine-3-sulfonic acid 5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl ester 
• 263842-97-3 pyridine-2-sulfonic acid 5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl ester 
• 263842-74-6 thiophene-2-sulfonic acid [5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-amide 
• 263842-75-7 pyridine-2-sulfonic acid [5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-amide 
• 263842-72-4 N-[5-tert-Butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-4-cyano-benzenesulfonamide 
• 263842-71-3 N-[5-tert-Butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-3-cyano-benzenesulfonamide 

Relevant articles and documents

Catalytic Radical Trifluoromethylalkynylation of Unactivated Alkenes

The trifluoromethylalkynylation of unactivated alkenes with alkynyl sulfones and Togni's reagent was developed. The reaction was catalyzed by 2,4,6-trimethylpyridine, leading to various β-trifluoromethylated alkynes under metal-free conditions with a broad substrate scope and wide functional group compatibility. A mechanism involving catalytic nonchain radical processes is proposed.

Chemoselective reduction of ?,￠-unsaturated carbonyl and carboxylic compounds by hydrogen iodide

The selective reduction of ?,￠-unsaturated carbonyl compounds was achieved to produce saturated carbonyl compounds with aqueous HI solution. The introduction of an aryl group at an ? or ￠ position efficiently facilitated the reduction with good yield. The reaction was applicable to compounds bearing carboxylic acids and halogen atoms. Through the investigation of the reaction mechanism, it was found that Michael-type addition of iodide occurred to produce ￠-iodo compounds followed by the reduction of C-I bond via anionic and radical paths.

Visible-Light-Promoted Catalytic Ring-Opening Isomerization of 1,2-Disubstituted Cyclopropanols to Linear Ketones

Isomerization to linear ketones is a valuable transformation of 1,2-disubstituted cyclopropanols proceeding through radical intermediates. Despite simplicity of this reaction, the known protocol required stoichiometric amounts of both an oxidant and a reducing agent. In this article, we report a catalytic isomerization of 1,2-disubstituted cyclopropanols to linear ketones enabled by the photoredox catalytic system consisting of an acridinium photocatalyst and diphenyl disulfide under irradiation with blue LEDs.