40504-79-8

Basic information

• Product Name: hydroxy-(3-trifluoromethyl-phenyl)-acetic acid ethyl ester
• Synonyms: hydroxy-(3-trifluoromethyl-phenyl)-acetic acid ethyl ester
• CAS NO: 40504-79-8
• Molecular Weight: 248.202
• Mol File: 40504-79-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: hydroxy-(3-trifluoromethyl-phenyl)-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: hydroxy-(3-trifluoromethyl-phenyl)-acetic acid ethyl ester(40504-79-8)
• EPA Substance Registry System: hydroxy-(3-trifluoromethyl-phenyl)-acetic acid ethyl ester(40504-79-8)

Safety Data

• Hazardous Substances Data: 40504-79-8(Hazardous Substances Data)

Upstream product

• 924-44-7 glyoxylic acid ethyl ester 
• 1423-26-3 (meta-(trifluoromethyl)phenyl)boronic acid 
• 402-26-6 3-(trifluoromethyl)phenylmagnesium bromide 
• 95-92-1 oxalic acid diethyl ester 

Downstream Products

• 349-10-0 2-Hydroxy-2-(3-trifluoromethylphenyl)ethanoic acid 
• 32957-06-5 2-amino-5-(3-trifluoromethyl-phenyl)-oxazol-4-one 

Relevant articles and documents

Enantioselective C-H Olefination of α-Hydroxy and α-Amino Phenylacetic Acids by Kinetic Resolution

Significant progress has been made in the past decade regarding the development of enantioselective C-H activation reactions by desymmetrization. However, the requirement for the presence of two chemically identical prochiral C-H bonds represents an inherent limitation in scope. Reported is the first example of kinetic resolution by a palladium(II)-catalyzed enantioselective C-H activation and C-C bond formation, thus significantly expanding the scope of enantioselective C-H activation reactions.