405058-67-5

Basic information

• Product Name: N-OXIDE-2,4-DIMETHYL-3-PYRIDINE CARBOXYLIC ACID ETHYL ESTER
• Synonyms: N-OXIDE-2,4-DIMETHYL-3-PYRIDINE CARBOXYLIC ACID ETHYL ESTER;3-Pyridinecarboxylicacid,2,4-dimethyl-,ethylester,1-oxide(9CI);ethyl 2,4-dimethyl-1-oxidopyridin-1-ium-3-carboxylate
• CAS NO: 405058-67-5
• Molecular Formula: C10H13NO3
• Molecular Weight: 195.22
• Product Categories: CARBOXYLICESTER
• Mol File: 405058-67-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 351.4°C at 760 mmHg
• Flash Point: 166.3°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 4.12E-05mmHg at 25°C
• Refractive Index: 1.515
• CAS DataBase Reference: N-OXIDE-2,4-DIMETHYL-3-PYRIDINE CARBOXYLIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: N-OXIDE-2,4-DIMETHYL-3-PYRIDINE CARBOXYLIC ACID ETHYL ESTER(405058-67-5)
• EPA Substance Registry System: N-OXIDE-2,4-DIMETHYL-3-PYRIDINE CARBOXYLIC ACID ETHYL ESTER(405058-67-5)

Safety Data

• Hazardous Substances Data: 405058-67-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H13NO3/c1-4-14-10(12)9-7(2)5-6-11(13)8(9)3/h5-6H,4H2,1-3H3

Upstream product

• 37669-78-6 ethyl 2,4-dimethylnicotinate 

Downstream Products

• 871492-83-0 6-chloro-N-(R)-{3-[4-(4-methoxy-phenylamino)-piperidin-1-yl]-butyl}-2,4-dimethyl-nicotinamide 
• 372156-99-5 3-carboxy-2,4-dimethylpyridine 1-oxide 

Relevant articles and documents

Design and synthesis of pyridin-2-ylmethylaminopiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication

A series of CCR5 antagonists were optimized for potent inhibition of R5 HIV-1 replication in peripheral blood mononuclear cells. Compounds that met acceptable ADME criteria, selectivity, human plasma protein binding, potency shift in the presence of α-glycoprotein were evaluated in rat and dog pharmacokinetics.

CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS

Tertiary amines containing a multiplicity of heteroaromatic substituents are useful as chemokine receptor modulators.