40523-35-1

Basic information

• Product Name: (3E)-3-benzylidene-2-methylisoindolin-1-one
• Synonyms: (3E)-3-benzylidene-2-methylisoindolin-1-one
• CAS NO: 40523-35-1
• Molecular Weight: 235.285
• Mol File: 40523-35-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (3E)-3-benzylidene-2-methylisoindolin-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3E)-3-benzylidene-2-methylisoindolin-1-one(40523-35-1)
• EPA Substance Registry System: (3E)-3-benzylidene-2-methylisoindolin-1-one(40523-35-1)

Safety Data

• Hazardous Substances Data: 40523-35-1(Hazardous Substances Data)

Upstream product

• 206365-69-7 3-(hydroxy(phenyl)methyl)-2-methylisoindolin-1-one 
• 110166-72-8 2-(2'-phenylethynyl)-N-methyl benzamide 
• 550-44-7 N-methylphthalimide 
• 100-52-7 benzaldehyde 
• 4702-13-0 N-phthaloylglycine 
• 13005-36-2 potassium phenylacetate 
• 5342-91-6 2-methylisoindolin-1-one 
• 144175-21-3 N-(diphenyloxophosphinyl)methyl-N-methyl-2-bromobenzamide 
• 95840-09-8 C₂₃H₁₉NOS 
• 122889-70-7 2-Bromo-N-methyl-N-phenylacetyl-benzamide 
• 4770-23-4 3-benzyl-3-hydroxy-2-methyl-1,3-dihydroisoindol-1(3H)-one 

Downstream Products

• 40523-36-2 (Z)-3-benzylidene-2-methyl-2,3-dihydro-1H-isoindolin-1-one 

Relevant articles and documents

Diastereoselective addition of metalated isoindolin-1-ones to aldehydes. Stereoselective preparation of (E)-3-arylideneisoindolin-1-ones

Lithiated isoindolinones react with aromatic aldehydes to afford 3-hydroxybenzyl derivatives with high diastereoselectivity. Dehydration of erythro and threo adducts through an E1cb mechanism gives rise indiscriminately to the (E)-arylideneisoindolinones.

Reductive coupling of phthalimides with ketones and aldehydes by low-valent titanium: One-pot synthesis of alkylideneisoindolin-1-ones

The reductive coupling of phthalimides with ketones and aldehydes by Zn-TiCl4 in THF gave two- and four-electron reduced products, 3-hydroxy-3-(1-hydroxyalkyl)isoindolin-1-ones and alkylideneisoindolin-1-ones, selectively by controlling the rea

Microphotochemistry: 4,4′-dimethoxybenzophenone mediated photodecarboxylation reactions involving phthalimides

A series of 4,4'-dimethoxybenzophenone mediated intra- and intermolecular photodecarboxylation reactions involving phthalimides have been examined under microflow conditions. Conversion rates, isolated yields and chemoselectivities were compared to analogous reactions in a batch photoreactor. In all cases investigated, the microreactions gave superior results thus proving the superiority of microphotochemistry over conventional technologies.