405231-20-1

Basic information

• Product Name: 1-[(1-acetyloxy-1-ethoxy)methyl]-4,6,7-trifluoroimidazo[4,5-c]pyridine
• CAS NO: 405231-20-1
• Molecular Weight: 289.214
• Mol File: 405231-20-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[(1-acetyloxy-1-ethoxy)methyl]-4,6,7-trifluoroimidazo[4,5-c]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(1-acetyloxy-1-ethoxy)methyl]-4,6,7-trifluoroimidazo[4,5-c]pyridine(405231-20-1)
• EPA Substance Registry System: 1-[(1-acetyloxy-1-ethoxy)methyl]-4,6,7-trifluoroimidazo[4,5-c]pyridine(405231-20-1)

Safety Data

• Hazardous Substances Data: 405231-20-1(Hazardous Substances Data)

Upstream product

• 6256-96-8 3,4-diamino-2,5,6-trifluoropyridine 
• 14036-06-7 diethoxymethyl acetate 

Downstream Products

• 405231-13-2 4,6,7-trifluoro-3-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)imidazo[4,5-c]pyridine 
• 405231-12-1 4,6,7-trifluoro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)imidazo[4,5-c]pyridine 
• 405230-95-7 4,6,7-trifluoroimidazo[4,5-c]pyridine 

Relevant articles and documents

Synthesis of halogen-substituted 3-deazaadenosine and 3-deazaguanosine analogues as potential antitumor/antiviral agents

Various 2-halogen-substituted analogues (38, 39, 43 and 44), 3-halogensubstituted analogues (51 and 52), and 2′,3′ -dihalogen- substituted analogues (57-60) of 3-deazaadenosine and 3-halogen-substituted analogues (61 and 62) of 3-deazaguanosine have been synthesized as potential anticancer and/or antiviral agents. Among these compounds, 3-deaza-3-bromoguanosine (62) showed significant cytotoxicity against L1210, P388, CCRF-CEM and B16F10 cell lines in vitro, producing IC50 values of 3, 7, 9 and 7μM, respectively. Several 3-deazaadenosine analogues (38, 51, 57 and 59) showed moderate to weak activity against hepatitis B virus.