405238-83-7 Usage
Description
[(2S,5R)-5-(2,6-diamino-9H-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]methanol is a chemical compound characterized by a furan ring with a hydroxymethyl group attached to it and a purine ring with two amino groups. It exhibits specific stereochemistry with the 2S and 5R configurations and is a derivative of the nucleoside adenosine. [(2S,5R)-5-(2,6-diamino-9H-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]methanol holds potential in pharmaceutical research, particularly for the development of antiviral drugs and nucleoside analogues. Its unique structure and functional groups make it a valuable compound for studying the interactions and mechanisms of action of nucleosides and related compounds in biological systems.
Uses
Used in Pharmaceutical Research:
[(2S,5R)-5-(2,6-diamino-9H-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]methanol is used as a key compound in the development of antiviral drugs and nucleoside analogues due to its adenosine derivative nature and specific structure. Its application in this field is driven by the need for novel antiviral agents and the potential of this compound to interact with biological systems in unique ways.
Used in Chemical Synthesis:
In the chemical synthesis industry, [(2S,5R)-5-(2,6-diamino-9H-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]methanol can be used as a building block or intermediate for the synthesis of more complex molecules with potential applications in various fields, including pharmaceuticals, agrochemicals, and materials science. Its unique functional groups and stereochemistry make it a versatile compound for synthetic chemistry.
Used in Biological Research:
[(2S,5R)-5-(2,6-diamino-9H-purin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]methanol is also used as a research tool in biological studies to investigate the interactions and mechanisms of action of nucleosides and related compounds. Its specific structure allows scientists to gain insights into the molecular basis of various biological processes and potentially identify new targets for therapeutic intervention.
Check Digit Verification of cas no
The CAS Registry Mumber 405238-83-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,5,2,3 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 405238-83:
(8*4)+(7*0)+(6*5)+(5*2)+(4*3)+(3*8)+(2*8)+(1*3)=127
127 % 10 = 7
So 405238-83-7 is a valid CAS Registry Number.
405238-83-7Relevant articles and documents
Structure-activity relationships of 2′-fluoro-2′,3′-unsaturated d-nucleosides as anti-hiv-1 agents
Lee, Kyeong,Choi, Yongseok,Gumina, Giuseppe,Zhou, Wen,Schinazi, Raymond F.,Chu, Chung K.
, p. 1313 - 1320 (2002)
We studied the structure-activity relationships of a series of 2′-fluoro-2′,3′-unsaturated D-nucleosides against HIV-1 in human peripheral blood mononuclear (PBM) cells. The target compounds 10-21 and 28-33 were prepared by N-glycosylation of the acetate
